Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAMP1 | O60894 | 1/20 | 0.53 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 5/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | RET | P07949 | 2/20 | 0.32 |
| ▸ | ROS1 | P08922 | 2/20 | 0.32 |
| ▸ | FLT3 | P36888 | 2/20 | 0.32 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.32 |
| ▸ | CCR10 | P46092 | 1/20 | 0.32 |
| ▸ | CALCA | P06881 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CCR3 | P51677 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5248991 | 0.83 | RAMP1 (0.59) | RAMP1CALCRLADRB2SLC6A5EPHX2 | |
| SCHEMBL3314750 | 0.83 | RAMP1 (0.59) | RAMP1CALCRLADRB2SLC6A5EPHX2 | |
| SCHEMBL3314758 | 0.83 | RAMP1 (0.59) | RAMP1CALCRLADRB2SLC6A5EPHX2 | |
| SCHEMBL3314129 | 0.82 | CALCRL (0.66) | RAMP1CALCRLADRB2SLC6A5EPHX2 | |
| SCHEMBL3314116 | 0.82 | CALCRL (0.66) | RAMP1CALCRLADRB2SLC6A5EPHX2 | |
| SCHEMBL3312077 | 0.81 | RAMP1 (0.60) | RAMP1CALCRLADRB2SLC6A5EPHX2 | |
| SCHEMBL3312081 | 0.81 | RAMP1 (0.60) | RAMP1CALCRLADRB2SLC6A5EPHX2 | |
| SCHEMBL4472276 | 0.79 | RAMP1 (0.56) | RAMP1CALCRLADRB2SLC6A5RET | |
| SCHEMBL4472279 | 0.78 | RAMP1 (0.55) | RAMP1CALCRLADRB2SLC6A5RET | |
| SCHEMBL4472287 | 0.78 | RAMP1 (0.55) | RAMP1CALCRLADRB2SLC6A5RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113411-A1 | Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113411-A1 | Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions | CALCRL, CALCR, CALCA | RAMP1 84/4885CALCRL 1/4885ADRB2 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.