Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19816455 | 1.00 | LMNA (0.52) | LMNATSHRTHRBEPHX1LPAR2 | |
| SCHEMBL9082561 | 1.00 | LMNA (0.52) | LMNATSHRTHRBEPHX1LPAR2 | |
| SCHEMBL19816767 | 0.98 | LMNA (0.48) | LMNATSHRTHRBEPHX1 | |
| SCHEMBL3291830 | 0.95 | LMNA (0.52) | LMNATSHRTHRBEPHX1LPAR2 | |
| SCHEMBL27959498 | 0.95 | LMNA (0.52) | LMNATSHRTHRBEPHX1LPAR2 | |
| SCHEMBL27959361 | 0.95 | LMNA (0.52) | LMNATSHRTHRBEPHX1LPAR2 | |
| SCHEMBL27959444 | 0.95 | LMNA (0.52) | LMNATSHRTHRBEPHX1LPAR2 | |
| SCHEMBL28811531 | 0.95 | LMNA (0.52) | LMNATSHRTHRBEPHX1LPAR2 | |
| SCHEMBL25287611 | 0.93 | LMNA (0.55) | LMNATSHRTHRBEPHX1 | |
| SCHEMBL6046666 | 0.93 | LMNA (0.55) | LMNATSHRTHRBEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100112208-A1 | Titania-Based Coating for Capillary Microextraction | MALIK ABDUL | 2010-05-06 | — | — | US | disclosed |
| US-7622191-B2 | also called in tube solid-phase microextraction; inorganic-organic hybrid coating of titania-polydimethylsiloxane; preconcentrates sample for high pressure liquid chromatography analysis; pH stability, retains extraction performance even after NaOH treatment | UNIVERSITY OF SOUTH FLORIDA (US) | 2009-11-24 | — | — | US | disclosed |
| US-20060013982-A1 | Titania-Based Coating for Capillary Microextraction | UNIVERSITY OF SOUTH FLORIDA (US) | 2006-01-19 | — | — | US | disclosed |