Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 7/20 | 0.51 |
| ▸ | BACE1 | P56817 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CCR3 | P51677 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22755783 | 1.00 | ACHE (0.60) | ACHEALDH1A1BCHEBACE1CYP1A2 | |
| SCHEMBL566825 | 1.00 | ACHE (0.60) | ACHEALDH1A1BCHEBACE1CYP1A2 | |
| SCHEMBL566826 | 1.00 | ACHE (0.60) | ACHEALDH1A1BCHEBACE1CYP1A2 | |
| SCHEMBL1337308 | 0.87 | ACHE (0.60) | ACHEALDH1A1BCHEBACE1CYP1A2 | |
| SCHEMBL31444680 | 0.87 | ACHE (0.60) | ACHEALDH1A1BCHEBACE1CYP1A2 | |
| SCHEMBL6941799 | 0.87 | ACHE (0.60) | ACHEALDH1A1BCHEBACE1CYP1A2 | |
| SCHEMBL11206512 | 0.87 | ACHE (0.60) | ACHEALDH1A1BCHEBACE1CYP1A2 | |
| SCHEMBL13887811 | 0.87 | ACHE (0.60) | ACHEALDH1A1BCHEBACE1CYP1A2 | |
| SCHEMBL6941807 | 0.87 | ACHE (0.60) | ACHEALDH1A1BCHEBACE1CYP1A2 | |
| Hydrochloric Acid SCHEMBL27564231 | 0.86 | ACHE (0.58) | ACHEALDH1A1BCHEBACE1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105661-A1 | CONDENSED PYRIDINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2010-04-29 | — | — | US | disclosed |
| EP-2123651-A1 | CONDENSED PYRIDINE COMPOUND | Astellas Pharma Inc. (JP) | 2009-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105661-A1 | CONDENSED PYRIDINE COMPOUND | JAK3, IRAK3, JAK1 | ACHE 4006/4885ALDH1A1 2375/4885BCHE 3651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.