⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11870215 | 0.91 | NOS1 (0.35) | — | |
| SCHEMBL11371796 | 0.86 | NOS1 (0.32) | — | |
| SCHEMBL11371793 | 0.86 | NOS1 (0.32) | — | |
| SCHEMBL4077677 | 0.85 | — | — | |
| SCHEMBL432351 | 0.80 | — | — | |
| SCHEMBL815076 | 0.80 | NOS1 (0.37) | — | |
| SCHEMBL15536154 | 0.77 | — | — | |
| SCHEMBL89861 | 0.75 | — | — | |
| SCHEMBL1080501 | 0.75 | — | — | |
| SCHEMBL815098 | 0.75 | NOS1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118110-B1 | CYCLOPROPYL FUSED INDOLOBENZAZEPINE HCV INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2012-07-25 | — | — | EP | claimed |
| EP-2118110-A1 | CYCLOPROPYL FUSED INDOLOBENZAZEPINE HCV INHIBITORS | Bristol-Myers Squibb Company (US) | 2009-11-18 | — | — | EP | claimed |
| US-7538102-B2 | Compounds for the treatment of Hepatitis C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-05-26 | — | — | US | claimed |
| US-20080248952-A1 | Substituted 6-Phenyl-7-Aminotriazolopyrimidines, Method for the Production Thereof, Their Use for Controlling Pathogenic Fungi, and Agents Containing These Compounds | BASF AKTIENGESELLSCHAFT (DE) | 2008-10-09 | — | — | US | claimed |
| US-20080226592-A1 | Compounds for the Treatment of Hepatitis C | BRISTOL-MYERS SQUIBB COMPANY | 2008-09-18 | — | — | US | claimed |
| WO-2008112851-A1 | CYCLOPROPYL FUSED INDOLOBENZAZEPINE HCV INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-09-18 | — | — | WO | claimed |
| EP-1765824-B1 | SUBSTITUTED 6-PHENYL-7-AMINO-TRIAZOLOPYRIMIDINES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE FOR CONTROLLING PATHOGENIC FUNGI, AND AGENTS CONTAINING THESE COMPOUNDS | BASF AG (DE) | 2008-01-09 | — | — | EP | claimed |
| EP-1765824-A1 | SUBSTITUTED 6-PHENYL-7-AMINO-TRIAZOLOPYRIMIDINES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE FOR CONTROLLING PATHOGENIC FUNGI, AND AGENTS CONTAINING THESE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-28 | — | — | EP | claimed |
| US-7196095-B2 | (Pyrimidinyl) (phenyl) substituted fused heteroaryl p38 inhibiting and PKG kinase inhibiting compounds | MERCK & CO., INC. (US) | 2007-03-27 | — | — | US | claimed |
| US-7078521-B2 | Process for the preparation of 9-amino substituted 9,10-dihydropyrrolo[2,1-b][1,3]benzotiazepines | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2006-07-18 | — | — | US | claimed |
| EP-1305318-A1 | PROCESS FOR THE PREPARATION OF 9-AMINO SUBSTITUTED 9,10-DIHYDROPYRROLO 2,1-B] 1,3]BENZOTIAZEPINES | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 2003-05-02 | — | — | EP | claimed |
| WO-2003000682-A1 | (PYRIMIDYL)(PHENYL)SUBSTITUTED FUSED HETEROARYL P38 INHIBITING AND PKG KINASE INHIBITING COMPOUNDS | MERCK & CO., INC. (US) | 2003-01-03 | — | — | WO | claimed |
| EP-1100803-B1 | PYRROLO [2,1-B] [1,3]BENZOTHIAZEPINES WITH ATYPICAL ANTIPSYCHOTIC ACTIVITY | SIGMA TAU IND FARMACEUTI (IT) | 2002-10-02 | — | — | EP | claimed |
| US-6391870-B2 | DOPAMINERGIC AGENT | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2002-05-21 | — | — | US | claimed |
| WO-2002010175-A1 | PYRROLO[2,1-b][1,3]BENZOTHIAZEPINES AND THEIR USE FOR THE PREPARATION OF MEDICAMENTS WITH ANTIPSYCHOTIC ACTIVITY | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2002-02-07 | — | — | WO | claimed |
| WO-2002010174-A1 | PROCESS FOR THE PREPARATION OF 9-AMINO SUBSTITUTED 9,10-DIHYDROPYRROLO [2,1-B][1,3]BENZOTIAZEPINES | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2002-02-07 | — | — | WO | claimed |
| US-20020006921-A1 | Pyrrolo {2,1-b}{1,3}benzothiazepines with atypical antipsychotic activity | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2002-01-17 | — | — | US | claimed |
| US-4234602-A | ANTIINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1980-11-18 | — | — | US | claimed |
| US-4179558-A | ANITINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1979-12-18 | — | — | US | claimed |
| US-4022781-A | ANTHELMINTIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1977-05-10 | — | — | US | claimed |