SCHEMBL3314742

SCHEMBL3314742

O=C(/C=C/c1ccc(O)cc1)OC(=O)/C=C/c1ccc(O)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.71
CA7 P43166 6/20 0.71
CA9 Q16790 6/20 0.71
CA14 Q9ULX7 6/20 0.71
CA1 P00915 5/20 0.71
CA2 P00918 4/20 0.71
TYR P14679 3/20 0.71
F3 P13726 2/20 0.65
CYP2D6 P10635 1/20 0.65
CYP2C9 P11712 1/20 0.65
HSD11B1 P28845 1/20 0.65
AKR1B10 O60218 5/20 0.65
AKR1B1 P15121 5/20 0.65
CA4 P22748 3/20 0.63
CA6 P23280 3/20 0.63
CA5A P35218 3/20 0.63
CA5B Q9Y2D0 3/20 0.63
PKM P14618 2/20 0.63
ESR1 P03372 1/20 0.63
CA3 P07451 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10891552 1.00 CA12 (0.71) CA12CA7CA9CA14CA1
SCHEMBL13837132 0.92 AKR1B10 (0.66) CA12CA7CA9CA14CA1
SCHEMBL28314102 0.90 CA12 (0.65) CA12CA7CA9CA14CA1
SCHEMBL11095177 0.88 CA12 (0.68) CA12CA7CA9CA14CA1
SCHEMBL8496464 0.85 CA12 (0.69) CA12CA7CA9CA14CA1
SCHEMBL7279952 0.83 CA12 (0.67) CA12CA7CA9CA14CA1
SCHEMBL7279950 0.83 CA12 (0.67) CA12CA7CA9CA14CA1
SCHEMBL2033991 0.83 CA12 (0.67) CA12CA7CA9CA14CA1
SCHEMBL5606482 0.83 CA12 (0.67) CA12CA7CA9CA14CA1
Methyl P-Hydroxycinnamate SCHEMBL28386655 0.83 CA12 (1.00) CA12CA7CA9CA14CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102590372-A Method for detecting types and contents of phenolic acid in flue-cured tobacco root system secretion UNIV YUNNAN AGRICULTURAL 2012-07-18 CN disclosed
US-20100086646-A1 PROBIOTIC-CONTAINING FOOD PRODUCT AND A PROTONATED WEAK MONOACID COMPAGNIE GERVAIS DANONE (FR) 2010-04-08 US disclosed