SCHEMBL3316213

SCHEMBL3316213

CC12CC3CC(C1)C(c1cc(Br)ccc1O[Si](C)(C)C(C)(C)C)C(C)(C3)C2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3311939 0.85 KMT2A (0.41)
SCHEMBL3312705 0.78 MEN1 (0.34)
SCHEMBL9334077 0.74 NPY1R (0.32)
SCHEMBL3316211 0.69 TSHR (0.30)
SCHEMBL25385726 0.67 NPY1R (0.33)
SCHEMBL404791 0.66 HDAC11 (0.36)
SCHEMBL6449169 0.66 PTGDR2 (0.51)
SCHEMBL3313281 0.65 HDAC11 (0.32)
SCHEMBL3316206 0.62 EPHX2 (0.31)
SCHEMBL2287094 0.61 RAB9A (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100113816-A1 METHOD FOR PREPARTION OF SUBSTITUTED ADAMANTYLARYMAGNESIUM HALIDES JSC GRINDEKS (LV) 2010-05-06 US disclosed
EP-2129679-A2 A METHOD FOR PREPARATION OF SUBSTITUTED ADAMANTYLARYLMAGNESIUM HALIDES Grindeks, a joint stock company (LV) 2009-12-09 EP disclosed
WO-2008080993-A2 A METHOD FOR PREPARATION OF SUBSTITUTED ADAMANTYLARYLMAGNESIUM HALIDES KALVINSH IVARS (LV) 2008-07-10 WO disclosed