Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 4/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSH | P09668 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3319700 | 1.00 | CCR2 (0.40) | CCR2KCNH2PARP1KDM2BCYP2D6 | |
| SCHEMBL3317297 | 1.00 | CCR2 (0.40) | CCR2KCNH2PARP1KDM2BCYP2D6 | |
| SCHEMBL20088227 | 0.90 | HRH3 (0.36) | CCR2KCNH2PARP1CYP2D6PARP2 | |
| SCHEMBL12095083 | 0.90 | HRH3 (0.36) | CCR2KCNH2PARP1CYP2D6PARP2 | |
| SCHEMBL16768020 | 0.85 | CCR2 (0.40) | CCR2KCNH2KDM2BCYP2D6GHSR | |
| SCHEMBL17190310 | 0.85 | KCNH2 (0.40) | CCR2KCNH2PARP1KDM2BCYP2D6 | |
| SCHEMBL29108912 | 0.85 | CCR2 (0.40) | CCR2KCNH2KDM2BCYP2D6GHSR | |
| SCHEMBL22606404 | 0.83 | KCNH2 (0.40) | CCR2KCNH2PARP1KDM2BCYP2D6 | |
| SCHEMBL18875745 | 0.83 | KCNH2 (0.40) | CCR2KCNH2PARP1KDM2BCYP2D6 | |
| SCHEMBL13402613 | 0.80 | TDP1 (0.49) | CCR2KCNH2PARP1KDM2BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100104659-A1 | BENZOPYRANOPYRAZOLES | 4SC AG (DE) | 2010-04-29 | — | — | US | claimed |
| US-20100104659-A1 | BENZOPYRANOPYRAZOLES | 4SC AG (DE) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100104659-A1 | BENZOPYRANOPYRAZOLES | BAX, BCL2, BAD | CCR2 3381/4885KCNH2 3671/4885PARP1 255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.