Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.47 |
| ▸ | KDM5A | P29375 | 8/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432470 | 0.88 | — | — | |
| SCHEMBL27972459 | 0.87 | LTA4H (0.42) | KDM4CKDM5ASOAT1MEN1FAAH | |
| SCHEMBL15223811 | 0.84 | KDM5A (0.37) | KDM4CKDM5ASOAT1MEN1FAAH | |
| SCHEMBL329451 | 0.83 | KDM4C (0.48) | KDM4CKDM5AMEN1KMT2ALMNA | |
| SCHEMBL8386761 | 0.82 | KDM5A (0.51) | KDM4CKDM5ASOAT1MEN1FAAH | |
| SCHEMBL3415138 | 0.81 | KDM5A (0.47) | KDM4CKDM5ALMNAALDH1A1KDM5C | |
| SCHEMBL8100472 | 0.81 | KDM5A (0.61) | KDM4CKDM5AMEN1KMT2AALDH1A1 | |
| SCHEMBL29641969 | 0.80 | S1PR2 (0.53) | KDM4CKDM5ASOAT1MEN1FAAH | |
| SCHEMBL29641943 | 0.80 | S1PR2 (0.53) | KDM4CKDM5ASOAT1MEN1FAAH | |
| SCHEMBL29642022 | 0.80 | S1PR2 (0.53) | KDM4CKDM5ASOAT1MEN1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100104659-A1 | BENZOPYRANOPYRAZOLES | 4SC AG (DE) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100104659-A1 | BENZOPYRANOPYRAZOLES | BAX, BCL2, BAD | KDM4C 2767/4885KDM5A 3033/4885SOAT1 3894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.