⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25004071 | 0.95 | PRMT3 (0.40) | — | |
| SCHEMBL22343848 | 0.92 | EPHX1 (0.46) | — | |
| SCHEMBL16475529 | 0.90 | EPHX1 (0.44) | — | |
| SCHEMBL22564674 | 0.90 | EPHX1 (0.50) | — | |
| SCHEMBL19245115 | 0.90 | EPHX1 (0.50) | — | |
| SCHEMBL13856009 | 0.90 | EPHX1 (0.44) | — | |
| SCHEMBL17001500 | 0.90 | EPHX1 (0.50) | — | |
| SCHEMBL1231390 | 0.86 | PRMT3 (0.50) | — | |
| SCHEMBL17804601 | 0.85 | PRMT3 (0.46) | — | |
| SCHEMBL10045279 | 0.83 | PRMT3 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3596075-B1 | AZAINDOLES AS INHIBITORS OF HPK1 | HOFFMANN LA ROCHE (CH) | 2023-10-11 | — | — | EP | disclosed |
| WO-2023073600-A1 | COMPOSITIONS FOR PREVENTING OR TREATING IDIOPATHIC PULMONARY FIBROSIS (IPF) | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-05-04 | — | — | WO | disclosed |
| WO-2023066190-A1 | COMPOUNDS AND THEIR USES AS GPR183 INHIBITORS | NANJING IMMUNOPHAGE BIOTECH CO., LTD (CN) | 2023-04-27 | — | — | WO | disclosed |
| US-11472807-B2 | Purine derivatives for use as medicament and for use in treating neurodegenerative or neuro-inflammatory disorders | Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) | 2022-10-18 | — | — | US | disclosed |
| US-20220296594-A1 | POTENTIATORS OF ANTIMICROBIAL AND/OR ANTIVIRAL AGENTS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-09-22 | — | — | US | disclosed |
| EP-2087910-B1 | Polymeric prodrugs | ASCENDIS PHARMA GMBH (DE) | 2022-05-04 | — | — | EP | disclosed |
| EP-2087910-B1 | Polymeric prodrugs | ASCENDIS PHARMA GMBH (DE) | 2022-05-04 | — | — | EP | disclosed |
| US-20210283264-A1 | Polymeric Prodrugs with a Self-Immolative Linker | ASCENDIS PHARMA GMBH (DE) | 2021-09-16 | — | — | US | disclosed |
| US-20210283264-A1 | Polymeric Prodrugs with a Self-Immolative Linker | ASCENDIS PHARMA GMBH (DE) | 2021-09-16 | — | — | US | disclosed |
| EP-3600307-B1 | COMPOSITIONS FOR USE IN METHODS OF INHIBITING PROTEIN KINASES | UNIV HOUSTON SYSTEM (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-1485377-B1 | PYRANONES USEFUL AS ATM INHIBITORS | KUDOS PHARM LTD (GB) | 2009-12-09 | — | — | EP | disclosed |
| EP-2087910-A2 | Polymeric prodrugs | Complex Biosystems GmbH (DE) | 2009-08-12 | — | — | EP | disclosed |
| EP-2087910-A2 | Polymeric prodrugs | Complex Biosystems GmbH (DE) | 2009-08-12 | — | — | EP | disclosed |
| US-20080241102-A1 | Polymeric Prodrug with a Self-Immolative Linker | COMPLEX BIOSYSTEMS GMBH (DE) | 2008-10-02 | — | — | US | disclosed |
| US-20080241102-A1 | Polymeric Prodrug with a Self-Immolative Linker | COMPLEX BIOSYSTEMS GMBH (DE) | 2008-10-02 | — | — | US | disclosed |
| US-20080241102-A1 | Polymeric Prodrug with a Self-Immolative Linker | COMPLEX BIOSYSTEMS GMBH (DE) | 2008-10-02 | — | — | US | disclosed |
| EP-1463733-B1 | MITOTIC KINESIN INHIBITORS | MERCK & CO INC (US) | 2007-09-05 | — | — | EP | disclosed |
| US-20070037834-A1 | Anti-inflammatory; cellular infiltration inhibition modulating activity on thymus and activation-regulated chemokine and macrophage-derived chemokine functions; inhibitory activities against binding of TARC and MDC to T cells; allergic disease, autoimmune disease, transplant, graft rejection | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2007-02-15 | — | — | US | disclosed |
| EP-0422858-A2 | Multifunctional viscosity index improver | EXXON CHEMICAL PATENTS INC. (US) | 1991-04-17 | — | — | EP | disclosed |
| US-4291150-A | INTERFACIAL POLYMERIZATION | GENERAL ELECTRIC CO. (US) | 1981-09-22 | — | — | US | disclosed |