Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12919161 | 0.83 | EPHX1 (0.35) | EPHX1SSTR4GAAATMMEN1 | |
| SCHEMBL1560446 | 0.82 | RECQL (0.31) | SMN1; SMN2 | |
| SCHEMBL879060 | 0.81 | MEN1 (0.33) | EPHX1SSTR4GAAMEN1ALDH1A1 | |
| SCHEMBL12812732 | 0.81 | EPHX1 (0.36) | EPHX1SSTR4GAACES2CES1 | |
| SCHEMBL12332296 | 0.81 | MEN1 (0.33) | EPHX1SSTR4ATMMEN1ALDH1A1 | |
| SCHEMBL27466122 | 0.80 | EPHX1 (0.36) | EPHX1SSTR4GAAATMMEN1 | |
| SCHEMBL25068217 | 0.79 | EPHX1 (0.35) | EPHX1SSTR4GAALMNACES2 | |
| SCHEMBL19558199 | 0.76 | SSTR4 (0.36) | EPHX1SSTR4GAASMN1; SMN2EPHX2 | |
| SCHEMBL14094050 | 0.76 | EPHX1 (0.33) | EPHX1SSTR4GAA | |
| SCHEMBL23795666 | 0.75 | EPHX1 (0.34) | EPHX1CES2CES1PDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0228272-A2 | Preparation of urethane substituted diacetylene monomers and polymers | GTE LABORATORIES INCORPORATED (US) | 1987-07-08 | — | — | EP | claimed |
| US-9199934-B2 | Alpha-hydroxyketones | BASF SE (DE) | 2015-12-01 | — | — | US | disclosed |
| EP-2129659-B1 | ALPHA-HYDROXYKETONES | BASF SE (DE) | 2013-05-29 | — | — | EP | disclosed |
| US-20100104979-A1 | ALPHA-HYDROXYKETONES | IGM GROUP B.V. (NL) | 2010-04-29 | — | — | US | disclosed |
| EP-0228272-A2 | Preparation of urethane substituted diacetylene monomers and polymers | GTE LABORATORIES INCORPORATED (US) | 1987-07-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100104979-A1 | ALPHA-HYDROXYKETONES | C9, C1R, CBR3 | EPHX1 1347/4885SSTR4 1943/4885GAA 4240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.