Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.33 |
| ▸ | JUN | P05412 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM6A | O15550 | 1/20 | 0.32 |
| ▸ | TET3 | O43151 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3318023 | 0.88 | FGFR3 (0.44) | FGFR3CDC7CSNK1A1TYRO3DYRK1B | |
| SCHEMBL1126390 | 0.86 | FGFR3 (0.49) | FGFR3CDC7APPCYP2C9ALDH1A1 | |
| SCHEMBL1126631 | 0.78 | FGFR3 (0.59) | FGFR3CDC7APPCYP2C9ALDH1A1 | |
| SCHEMBL3316159 | 0.77 | MYC (0.41) | FGFR3CSNK1A1TYRO3DYRK1BALDH1A1 | |
| SCHEMBL17023018 | 0.70 | FGFR3 (0.45) | FGFR3CDC7APPCYP2C9ALDH1A1 | |
| SCHEMBL4332010 | 0.70 | FGFR3 (0.53) | FGFR3ALDH1A1KMT2AKDM4EL3MBTL1 | |
| Biphenyl SCHEMBL27718930 | 0.67 | CSNK1A1 (0.49) | CSNK1A1TYRO3DYRK1BALDH1A1KMT2A | |
| SCHEMBL3316051 | 0.67 | FGFR3 (0.51) | FGFR3 | |
| SCHEMBL15025427 | 0.66 | APP (0.50) | APPCYP2C9ALDH1A1RAB9AHSD17B10 | |
| SCHEMBL1126238 | 0.66 | KDM4E (0.52) | ALDH1A1KMT2ARAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105667-A1 | Quinoxaline- and Quinoline-Carboxamide Derivatives | NOVARTIS AG | 2010-04-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105667-A1 | Quinoxaline- and Quinoline-Carboxamide Derivatives | ABL1, NQO2, MAP4K5 | FGFR3 1515/4885CDC7 927/4885CSNK1A1 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.