Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 15/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12999350 | 0.82 | HDAC1 (0.54) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL2566024 | 0.75 | HDAC1 (0.53) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL3290596 | 0.73 | HDAC1 (0.42) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL2568942 | 0.73 | HDAC1 (0.70) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL22190399 | 0.72 | HDAC1 (0.90) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL22849745 | 0.70 | HDAC1 (1.00) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL2563898 | 0.69 | HDAC1 (0.56) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL9665149 | 0.69 | HDAC1 (0.97) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL14177653 | 0.66 | KMT2A (0.44) | — | |
| SCHEMBL6386199 | 0.66 | HDAC1 (0.88) | HDAC1HDAC6HDAC3HDAC2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723376-B2 | 2-oxo-heterocyclic compounds and pharmaceutical compositions | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2010-05-25 | — | — | US | disclosed |