Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.59 |
| ▸ | TFEB | P19484 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.51 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.51 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3300830 | 0.94 | NFE2L2 (0.60) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL13296131 | 0.94 | NFE2L2 (0.60) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL20378725 | 0.89 | KDM4E (0.59) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL8542378 | 0.89 | KDM4E (0.59) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL5856634 | 0.84 | NFE2L2 (0.56) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL5856631 | 0.84 | NFE2L2 (0.56) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL27733948 | 0.84 | KDM4E (0.54) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL11826024 | 0.83 | KDM4E (0.64) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL11826019 | 0.83 | KDM4E (0.64) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL12749161 | 0.82 | NFE2L2 (0.50) | NFE2L2TFEBKDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732365-B2 | Enantioselective amination and etherification | YALE UNIVERSITY (US) | 2010-06-08 | — | — | US | disclosed |
| US-20060199728-A1 | Enantioselective amination and etherification | YALE UNIVERSITY (US) | 2006-09-07 | — | — | US | disclosed |
| WO-2004024684-A2 | ENANTIOSELECTIVE AMINATION AND ETHERIFICATION | YALE UNIVERSITY (US) | 2004-03-25 | — | — | WO | disclosed |