SCHEMBL332045

SCHEMBL332045

CC=CC(=O)OCCC[Si](C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.48
HCAR2 Q8TDS4 5/20 0.43
MAPT P10636 1/20 0.38
RAB9A P51151 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TSHR P16473 2/20 0.37
HPGD P15428 1/20 0.37
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
GSTP1 P09211 1/20 0.34
APP P05067 5/20 0.33
PRKCA P17252 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4630430 0.90 ATM (0.59) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL28667982 0.90 ATM (0.59) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL373595 0.90 ATM (0.59) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL29215837 0.88 ATM (0.42) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL10398160 0.87 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL932962 0.87 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL3304908 0.87 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL12095075 0.86 ATM (0.50) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL8672226 0.85 ATM (0.46) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL17138286 0.85 ATM (0.46) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118240140-A Solid phase cleaning agent while drilling for oil-based drilling fluid and preparation method and application thereof 中石化石油工程技术服务有限公司 2024-06-25 CN claimed
CN-114904499-B Chiral Co-L-GG doped organic polymer capillary monolithic column 闽江学院 2024-03-12 CN claimed
CN-117263573-B Asphalt concrete and preparation method thereof 河北磊得新型建材科技有限公司 2024-01-30 CN claimed
CN-117263573-A Asphalt concrete and preparation method thereof 河北磊得新型建材科技有限公司 2023-12-22 CN claimed
CN-117263607-A Super-retarding concrete and preparation method thereof 杭州汉特建材有限公司 2023-12-22 CN claimed
CN-116102284-A Preparation method of thermoplastic elastic material for oil well cement 中石化石油工程技术服务有限公司 2023-05-12 CN claimed
CN-115260985-A Two-component low-viscosity high-heat-conductivity pouring sealant and preparation method and application thereof 韦尔通(厦门)科技股份有限公司 2022-11-01 CN claimed
CN-114904499-A Chiral Co-L-GG doped organic polymer capillary monolithic column 闽江学院 2022-08-16 CN claimed
CN-114752190-A PET heat-sealing auxiliary agent, PET heat-sealing sheet and preparation method thereof 东莞鸿冠新材料科技有限公司 2022-07-15 CN claimed
CN-114644480-A Elastic and tough cement paste containing thermoplastic elastic material and preparation method thereof 中石化石油工程技术服务有限公司 2022-06-21 CN claimed
US-20040097652-A1 Flow-and-leveling agents for waterborne coatings KAWASE MASAFUMI (JP) 2004-05-20 US claimed
EP-1417209-A1 HIGH BOILING INHIBITORS FOR DISTILLABLE, POLYMERIZABLE MONOMERS Crompton Corporation (US) 2004-05-12 EP claimed
US-6642335-B2 Flow-and-leveling agents are (meth)acrylic acid ester based copolymers containing a trimethylsilyl and tris/trimethylsiloxy/silyl groups KUSUMOTO CHEMICALS LTD (JP) 2003-11-04 US claimed
US-20030105228-A1 Flow-and-leveling agents for waterborne coatings KUSUMOTO CHEMICALS, LTD. 2003-06-05 US claimed
US-20030100692-A1 Flow-and-leveling agents for powder coatings KUSUMOTO CHEMICALS, LTD. 2003-05-29 US claimed
US-20030065177-A1 High boiling inhibitors for distillable, polymerizable monomers CROMPTON CORPORATION, A CORPORATION OF THE STATE OF DELAWARE 2003-04-03 US claimed
WO-2003014130-A1 HIGH BOILING INHIBITORS FOR DISTILLABLE, POLYMERIZABLE MONOMERS CROMPTON CORPORATION (US) 2003-02-20 WO claimed
EP-1266913-A2 Flow-and-leveling agents for powder coatings Kusumoto Chemicals, Ltd. (JP) 2002-12-18 EP claimed
EP-1266914-A1 Flow-and-leveling agents for waterborne coatings Kusumoto Chemicals, Ltd. (JP) 2002-12-18 EP claimed
US-6475347-B1 High boiling inhibitors for distillable, polymerizable monomers CROMPTON CORPORATION 2002-11-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030065177-A1 High boiling inhibitors for distillable, polymerizable monomers ROS1, POLR1A, ACP1 ATM 666/4885HCAR2 4292/4885MAPT 3285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.