SCHEMBL17138286

SCHEMBL17138286

CC=CC(=O)OCCC[Si](C)(Br)Br

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.46
HCAR2 Q8TDS4 4/20 0.41
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TSHR P16473 2/20 0.35
HPGD P15428 1/20 0.35
ALDH1A1 P00352 1/20 0.34
CYP3A4 P08684 1/20 0.34
GSTP1 P09211 1/20 0.33
APP P05067 5/20 0.31
PRKCA P17252 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8672226 0.89 ATM (0.46) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL1225013 0.87 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL332045 0.85 ATM (0.48) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL26094895 0.84 ATM (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL3304908 0.84 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL10398160 0.84 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL932962 0.84 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL12095075 0.83 ATM (0.50) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL26095997 0.83 HCAR2 (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL26095195 0.83 HCAR2 (0.44) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2930177-B1 PREPARATION OF SILAZANE COMPOUND SHINETSU CHEMICAL CO (JP) 2018-04-25 EP disclosed
US-9416147-B2 Preparation of silazane compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-08-16 US disclosed
EP-2930177-A1 Preparation of silazane compound Shin-Etsu Chemical Co., Ltd. (JP) 2015-10-14 EP disclosed
US-20150284414-A1 PREPARATION OF SILAZANE COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150284414-A1 PREPARATION OF SILAZANE COMPOUND SLTM, SKP2, BCAT2 ATM 409/4885HCAR2 3706/4885MAPT 31/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.