Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 2/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10284334 | 0.89 | KDM4E (0.49) | KDM4ESMN1; SMN2PTGDR2LMNANPC1 | |
| SCHEMBL3297610 | 0.84 | KDM4E (0.54) | KDM4ESMN1; SMN2GRM2PTGDR2LMNA | |
| SCHEMBL10284333 | 0.84 | KDM4E (0.47) | KDM4ESMN1; SMN2LMNAMEN1ALDH1A1 | |
| SCHEMBL3303954 | 0.83 | KDM4E (0.53) | KDM4ESMN1; SMN2PTGDR2LMNANPC1 | |
| SCHEMBL27910474 | 0.82 | KDM4E (0.34) | KDM4EGRM2MALT1NPC1ALDH1A1 | |
| SCHEMBL20021122 | 0.82 | KDM4E (0.52) | KDM4ESMN1; SMN2GRM2PTGDR2LMNA | |
| SCHEMBL20020768 | 0.82 | CNR1 (0.45) | KDM4ESMN1; SMN2MALT1PTGDR2NPC1 | |
| SCHEMBL3323941 | 0.81 | KDM4E (0.51) | KDM4ESMN1; SMN2PTGDR2LMNADHODH | |
| SCHEMBL20021183 | 0.81 | KDM4E (0.44) | KDM4ESMN1; SMN2GRM2PTGDR2LMNA | |
| SCHEMBL3314187 | 0.81 | KDM4E (0.50) | KDM4ESMN1; SMN2PTGDR2LMNADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003498-A1 | 2 -QUINOLINYL- ACETIC ACID DERIVATIVES AS HIV ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-01-05 | — | — | WO | disclosed |