SCHEMBL3322085

SCHEMBL3322085

O=C1NC(=O)N2CCCCC12

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
KDM4E B2RXH2 5/20 0.50
MAPT P10636 4/20 0.50
GAA P10253 1/20 0.50
KMT2A Q03164 4/20 0.48
MEN1 O00255 3/20 0.48
PARP1 P09874 4/20 0.47
HPGD P15428 3/20 0.43
ALOX15 P16050 2/20 0.43
HSD17B10 Q99714 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
CHEK1 O14757 1/20 0.39
MAP2K1 Q02750 1/20 0.39
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4538351 0.93 ALDH1A1 (0.56) ALDH1A1KDM4EMAPTGAAKMT2A
SCHEMBL21359608 0.93 ALDH1A1 (0.56) ALDH1A1KDM4EMAPTGAAKMT2A
SCHEMBL3457347 0.75 ALDH1A1 (0.51) ALDH1A1KDM4EMAPTGAAKMT2A
SCHEMBL15835183 0.75 ALDH1A1 (0.51) ALDH1A1KDM4EMAPTGAAKMT2A
SCHEMBL8080267 0.74 ALDH1A1 (0.91) ALDH1A1KDM4EMAPTGAAKMT2A
SCHEMBL3519704 0.74 ALDH1A1 (0.43) ALDH1A1KDM4EMAPTGAAKMT2A
SCHEMBL1189351 0.74 ALDH1A1 (0.43) ALDH1A1KDM4EMAPTGAAKMT2A
SCHEMBL3519708 0.74 ALDH1A1 (0.43) ALDH1A1KDM4EMAPTGAAKMT2A
SCHEMBL15523572 0.73 GAA (0.88) ALDH1A1KDM4EMAPTGAAKMT2A
SCHEMBL5710904 0.71 ALDH1A1 (0.62) ALDH1A1KDM4EMAPTGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114085219-B Synthesis of (1S, 6R) -8-benzyl-7, 9-dioxo-2, 8-diazabicyclo [4.3.0] nonane 武汉理工大学 2023-08-01 CN claimed
CN-114085219-A Synthesis of (1S,6R) -8-benzyl-7, 9-dioxo-2, 8-diazabicyclo [4.3.0] nonane 武汉理工大学 2022-02-25 CN claimed
EP-4743459-A1 BICYCLIC AND MONOCYCLIC TRPA1 INHIBITORS D.E. Shaw Research, LLC (US) 2026-05-20 EP disclosed
WO-2025014922-A1 BICYCLIC AND MONOCYCLIC TRPA1 INHIBITORS D. E. SHAW RESEARCH, LLC (US) 2025-01-16 WO disclosed
CN-118344315-A Preparation and application of trifluoro thioether (sulfoxide) aromatic amine derivative 顺毅股份有限公司 2024-07-16 CN disclosed
CN-114085219-B Synthesis of (1S, 6R) -8-benzyl-7, 9-dioxo-2, 8-diazabicyclo [4.3.0] nonane 武汉理工大学 2023-08-01 CN disclosed
CN-114085219-A Synthesis of (1S,6R) -8-benzyl-7, 9-dioxo-2, 8-diazabicyclo [4.3.0] nonane 武汉理工大学 2022-02-25 CN disclosed
CN-114085219-A Synthesis of (1S,6R) -8-benzyl-7, 9-dioxo-2, 8-diazabicyclo [4.3.0] nonane 武汉理工大学 2022-02-25 CN disclosed
EP-2144885-B1 IMIDAZOLIDINE CARBOXAMIDE DERIVATIVES AS LIPASE AND PHOSPHOLIPASE INHIBITORS SANOFI SA (FR) 2016-06-29 EP disclosed
US-8735437-B2 Imidazolidine carboxamide derivatives as lipase and phospholipase inhibitors SANOFI (FR) 2014-05-27 US disclosed
EP-2492322-A1 Ink composition, image forming method, and printed material Fujifilm Corporation (JP) 2012-08-29 EP disclosed
WO-1986005096-A1 PROTEIN ABSORPTION ENHANCING AGENTS SURVIVAL TECHNOLOGY, INC. (US) 1986-09-12 WO disclosed
EP-0192660-A1 ABSORPTION ENHANCING AGENTS. SURVIVAL TECHNOLOGY (US) 1986-09-03 EP disclosed
EP-0191814-A1 PROTEIN ABSORPTION ENHANCING AGENTS. SURVIVAL TECHNOLOGY (US) 1986-08-27 EP disclosed
EP-0191056-A1 t-PA COMPOSITION AND METHOD OF GETTING INTO BLOOD STREAM SURVIVAL TECHNOLOGY, INC. (US) 1986-08-20 EP disclosed
WO-1986001104-A1 t-PA COMPOSITION AND METHOD OF GETTING INTO BLOOD STREAM SURVIVAL TECHNOLOGY, INC. (US) 1986-02-27 WO disclosed
WO-1986001110-A1 ABSORPTION ENHANCING AGENTS SURVIVAL TECHNOLOGY, INC. (US) 1986-02-27 WO disclosed
WO-1986001109-A1 PROTEIN ABSORPTION ENHANCING AGENTS SURVIVAL TECHNOLOGY, INC. (US) 1986-02-27 WO disclosed
US-4436910-A SAPONIFICATION DEGUSSA AKTIENGESELLSCHAFT (DE) 1984-03-13 US disclosed
US-4012259-A DICARBONYL METHYLENE GROUP ON A 2,5-DIOXO-1-IMIDAZOLIDINE IS A YELLOW COUPLER FUJI PHOTO FILM CO., LTD. (JA) 1977-03-15 US disclosed