Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.46 |
| ▸ | CES2 | O00748 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8467773 | 0.93 | CES2 (0.48) | CES1CES2HSD17B10TDP1ALDH1A1 | |
| SCHEMBL4783263 | 0.91 | CES2 (0.50) | CES1CES2HSD17B10TDP1ALDH1A1 | |
| SCHEMBL7024041 | 0.91 | CES2 (0.50) | CES1CES2HSD17B10TDP1ALDH1A1 | |
| SCHEMBL27709375 | 0.91 | CES2 (0.50) | CES1CES2HSD17B10TDP1ALDH1A1 | |
| SCHEMBL27729873 | 0.91 | CES2 (0.50) | CES1CES2HSD17B10TDP1ALDH1A1 | |
| SCHEMBL27709290 | 0.91 | CES2 (0.50) | CES1CES2HSD17B10TDP1ALDH1A1 | |
| SCHEMBL5318003 | 0.91 | CES2 (0.50) | CES1CES2HSD17B10TDP1ALDH1A1 | |
| SCHEMBL218025 | 0.91 | CES2 (0.50) | CES1CES2HSD17B10TDP1ALDH1A1 | |
| SCHEMBL887957 | 0.85 | — | — | |
| SCHEMBL19480 | 0.85 | CES1 (0.41) | CES1CES2ALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3155084-B1 | DISHWASHER DETERGENT FRAGRANCE COMPOSITION | GIVAUDAN SA (CH) | 2018-11-07 | — | — | EP | claimed |
| US-10920178-B2 | Dishwasher detergent fragrance composition | GIVAUDAN SA (CH) | 2021-02-16 | — | — | US | disclosed |
| US-10695449-B2 | Catalytic radiofluorination | THE GENERAL HOSPITAL CORPORATION (US) | 2020-06-30 | — | — | US | disclosed |
| US-20190264143-A1 | Dishwasher Detergent Fragrance Composition | GIVAUDAN S.A. (CH) | 2019-08-29 | — | — | US | disclosed |
| US-20190054198-A1 | CATALYTIC RADIOFLUORINATION | THE GENERAL HOSPITAL CORPORATION | 2019-02-21 | — | — | US | disclosed |
| EP-3155084-B1 | DISHWASHER DETERGENT FRAGRANCE COMPOSITION | GIVAUDAN SA (CH) | 2018-11-07 | — | — | EP | disclosed |
| EP-3155084-A1 | DISHWASHER DETERGENT FRAGRANCE COMPOSITION | Givaudan S.A. (CH) | 2017-04-19 | — | — | EP | disclosed |
| US-20170081619-A1 | Dishwasher Detergent Fragrance Composition | GIVAUDAN S.A. (CH) | 2017-03-23 | — | — | US | disclosed |
| WO-2015189296-A1 | DISHWASHER DETERGENT FRAGRANCE COMPOSITION | GIVAUDAN SA (CH) | 2015-12-17 | — | — | WO | disclosed |
| US-20150283273-A1 | Catalytic Radiofluorination | THE GENERAL HOSPITAL CORPORATION | 2015-10-08 | — | — | US | disclosed |
| US-20120207677-A1 | CATALYTIC RADIOFLUORINATION | THE GENERAL HOSPITAL CORPORATION | 2012-08-16 | — | — | US | disclosed |
| EP-2388017-A2 | Catalytic radiofluorination | The General Hospital Corporation (US) | 2011-11-23 | — | — | EP | disclosed |
| US-20100215578-A1 | Catalytic Radiofluorination | THE GENERAL HOSPITAL CORPORATION (US) | 2010-08-26 | — | — | US | disclosed |
| US-20100215578-A1 | Catalytic Radiofluorination | THE GENERAL HOSPITAL CORPORATION (US) | 2010-08-26 | — | — | US | disclosed |
| US-7632485-B2 | Catalytic radiofluorination | MASSACHUSETTS GENERAL HOSPITAL (US) | 2009-12-15 | — | — | US | disclosed |
| WO-2008022319-A2 | CATALYTIC RADIOFLUORINATION | THE GENERAL HOSPITAL CORPORATION (US) | 2008-02-21 | — | — | WO | disclosed |
| US-6962767-B2 | Acetal compound, polymer, resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-11-08 | — | — | US | disclosed |
| US-20030153706-A1 | Acetal compound, polymer, resist composition and patterning response | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2003-08-14 | — | — | US | disclosed |
| US-6515149-B2 | Exposure to high energy radiation | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2003-02-04 | — | — | US | disclosed |
| US-20020132970-A1 | Acetal compound, polymer, resist composition and patterning response | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190054198-A1 | CATALYTIC RADIOFLUORINATION | KCNJ5, KCNQ5, KCNK18 | CES1 1822/4885CES2 437/4885HSD17B10 3609/4885 |
| US-20150283273-A1 | Catalytic Radiofluorination | KCNJ5, KCNQ5, KCNK18 | CES1 1822/4885CES2 437/4885HSD17B10 3609/4885 |
| US-10695449-B2 | Catalytic radiofluorination | KCNJ5, KCNQ5, KCNK18 | CES1 1822/4885CES2 437/4885HSD17B10 3609/4885 |
| US-20100215578-A1 | Catalytic Radiofluorination | KCNJ5, KCNQ5, KCNK18 | CES1 1822/4885CES2 437/4885HSD17B10 3609/4885 |
| US-20120207677-A1 | CATALYTIC RADIOFLUORINATION | ARSA, STS, KCNK18 | CES1 608/4885CES2 202/4885HSD17B10 2541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.