Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3323523 | 1.00 | TSHR (0.49) | TSHRHPGDPPARGSMN1; SMN2CA9 | |
| SCHEMBL4624012 | 0.86 | SMN1; SMN2 (0.42) | TSHRHPGDPPARGSMN1; SMN2ALDH1A1 | |
| SCHEMBL4624008 | 0.86 | SMN1; SMN2 (0.42) | TSHRHPGDPPARGSMN1; SMN2ALDH1A1 | |
| SCHEMBL1758939 | 0.85 | TSHR (0.54) | TSHRHPGDSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL21901873 | 0.83 | TSHR (0.51) | TSHRHPGDPPARGSMN1; SMN2ROCK2 | |
| SCHEMBL4623289 | 0.82 | TSHR (0.54) | TSHRHPGDSMN1; SMN2CA9ALDH1A1 | |
| SCHEMBL4624575 | 0.82 | TSHR (0.45) | TSHRHPGDPPARGSMN1; SMN2ROCK2 | |
| SCHEMBL3326140 | 0.81 | TSHR (0.42) | TSHRHPGDPPARGSMN1; SMN2ROCK2 | |
| SCHEMBL3326135 | 0.81 | TSHR (0.42) | TSHRHPGDPPARGSMN1; SMN2ROCK2 | |
| SCHEMBL3324965 | 0.80 | TSHR (0.41) | TSHRHPGDPPARGSMN1; SMN2ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9743667-B2 | Substituted benzene fungicides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-08-29 | — | — | US | disclosed |
| US-9198433-B2 | Substituted benzene fungicides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-12-01 | — | — | US | disclosed |
| US-20150335023-A1 | SUBSTITUTED BENZENE FUNGICIDES | FMC CORPORATION | 2015-11-26 | — | — | US | disclosed |
| US-20140323436-A1 | SUBSTITUTED BENZENE FUNGICIDES | FMC CORPORATION | 2014-10-30 | — | — | US | disclosed |
| US-8822521-B2 | Substituted benzene fungicides | E I DU PONT DE NEMOURS AND COMPANY (DE) | 2014-09-02 | — | — | US | disclosed |
| EP-2129225-B1 | SUBSTITUTED BENZENE FUNGICIDES | DU PONT (US) | 2012-12-05 | — | — | EP | disclosed |
| US-20100120714-A1 | SUBSTITUTED BENZENE FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-05-13 | — | — | US | disclosed |
| EP-2129225-A2 | SUBSTITUTED BENZENE FUNGICIDES | E. I. Du Pont de Nemours and Company (US) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008124092-A2 | SUBSTITUTED BENZENE FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-16 | — | — | WO | disclosed |
| EP-1201648-B1 | CARBAMATE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL BACTERICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2008-04-02 | — | — | EP | disclosed |
| US-6812229-B1 | OXIME SUBSTITUTED PHENYL; RAIN-FAST WITHOUT CROP DAMAGE; CUCUMBER DOWNY MILDEW, APPLE SCAB, WHEAT POWDERY MILDEW, RICE BLAST, CUCUMBER GRAY MOLD, RICE SHEATH BLIGHT, WHEAT BROWN LEAF RUST, WHEAT SEPTORIA LEAF BLOTCH AND CUCUMBER STEM ROT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-11-02 | — | — | US | disclosed |
| EP-1201648-A1 | CARBAMATE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL BACTERICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2002-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150335023-A1 | SUBSTITUTED BENZENE FUNGICIDES | NR0B1, CBR3, NR0B2 | TSHR 1053/4885HPGD 4667/4885PPARG 2765/4885 |
| US-20140323436-A1 | SUBSTITUTED BENZENE FUNGICIDES | NR0B1, CBR3, NR0B2 | TSHR 1053/4885HPGD 4667/4885PPARG 2765/4885 |
| US-20100120714-A1 | SUBSTITUTED BENZENE FUNGICIDES | NR0B1, CBR3, NR0B2 | TSHR 1039/4885HPGD 4707/4885PPARG 2815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.