SCHEMBL332468

SCHEMBL332468

O=C=NCCCCCN=C=S

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 5/20 0.58
MIF P14174 4/20 0.58
GSK3B P49841 1/20 0.54
TRPA1 O75762 8/20 0.52
KEAP1 Q14145 2/20 0.50
NFE2L2 Q16236 2/20 0.50
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
TP53 P04637 1/20 0.50
BACH1 O14867 1/20 0.50
MAFK O60675 1/20 0.50
EGFR P00533 1/20 0.50
PTGS2 P35354 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3906746 1.00 NAAA (0.58) NAAAMIFGSK3BTRPA1KEAP1
SCHEMBL332767 1.00 NAAA (0.58) NAAAMIFGSK3BTRPA1KEAP1
SCHEMBL3906512 0.97 MIF (0.54) NAAAMIFGSK3BTRPA1KEAP1
SCHEMBL332039 0.92
SCHEMBL3916967 0.86
SCHEMBL10809632 0.86 MIF (0.38) NAAAMIFGSK3BTRPA1KEAP1
SCHEMBL8742957 0.86 MIF (0.38) NAAAMIFGSK3BTRPA1KEAP1
SCHEMBL1233523 0.86 NAAA (0.74) NAAAMIFGSK3BTRPA1KEAP1
SCHEMBL4251350 0.86 MIF (0.38) NAAAMIFGSK3BTRPA1KEAP1
SCHEMBL15038 0.86 MIF (0.38) NAAAMIFGSK3BTRPA1KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230120549-A1 Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same PPG INDUSTRIES OHIO, INC. 2023-04-20 US disclosed
US-11472912-B2 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2022-10-18 US disclosed
US-20220119581-A1 Aircraft Windows PPG INDUSTRIES, INC. 2022-04-21 US disclosed
US-11248083-B2 Aircraft windows PPG INDUSTRIES OHIO, INC. (US) 2022-02-15 US disclosed
CN-108690547-B Polyurethane adhesive for rubber shoes and preparation method and application thereof 广东铭宸工贸有限公司 2021-01-01 CN disclosed
CN-108753142-B Surface treating agent for rubber shoes as well as preparation method and application of surface treating agent 玉环德谷新材料科技有限公司 2020-11-17 CN disclosed
US-20200165375-A1 \"Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same\ PPG INDUSTRIES OHIO, INC. 2020-05-28 US disclosed
US-10590230-B2 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2020-03-17 US disclosed
US-20200071451-A1 Aircraft Windows PPG INDUSTRIES, INC. 2020-03-05 US disclosed
CN-108753142-A A kind of rubber boots surface conditioning agent and its preparation method and application 董大樵 2018-11-06 CN disclosed
EP-0528590-A1 Mercapto compound, its preparation process, and sulfur-containing urethane resins and lenses using the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-02-24 EP disclosed
EP-0506315-A2 Optical urethane resins and plastic lenses comprising the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-30 EP disclosed
EP-0505150-A1 Stabilizing method of isocyanate compounds and isocyanate compositions stabilized thereby MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-23 EP disclosed
US-5087758-A Polythiourethane monomer MITSUI TOATSU CHEMICALS, INC. (JP) 1992-02-11 US disclosed
EP-0378895-A1 A mercapto compound, a high refractive index resin and lens and a process for preparing them MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-07-25 EP disclosed
CN-1043498-A Mercapto compound, high refractive index resin and lens, and process for producing them MITSUI TOATSU CHEMICALS (JP) 1990-07-04 CN disclosed
US-4933352-A Bi-functional carbamates of 2-ureado-pyridine compounds THEODOROPULOS SPYROS (US) 1990-06-12 US disclosed
US-4873318-A Oxazine-ureas and thiazine urea chromophors THEODOROPULOS SPYROS (US) 1989-10-10 US disclosed
EP-0319620-A1 Novel oxazines-ureas and thiazine urea chromophors VIOMEDICS INC. (US) 1989-06-14 EP disclosed
US-4714763-A Novel oxazine-ureas and thiazine urea chromophors as fluorescent labels VIOMEDICS INC. (US) 1987-12-22 US disclosed