Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 5/20 | 0.38 |
| ▸ | MMP13 | P45452 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | ALPG | P10696 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15494050 | 0.86 | MEN1 (0.40) | MEN1KMT2AMAPTPOLBMMP13 | |
| SCHEMBL28511883 | 0.79 | MEN1 (0.40) | MEN1KMT2AMAPTPOLBMMP13 | |
| SCHEMBL3326021 | 0.79 | MEN1 (0.42) | MEN1KMT2AMAPTPOLBMMP13 | |
| Sulfuric Acid SCHEMBL28528641 | 0.78 | MEN1 (0.39) | MEN1KMT2AMAPTPOLBMMP13 | |
| SCHEMBL6834722 | 0.75 | MEN1 (0.39) | MEN1KMT2AMAPTPOLBMMP13 | |
| SCHEMBL28523723 | 0.75 | MAPT (0.37) | MEN1KMT2AMAPTPOLBMMP13 | |
| SCHEMBL28515181 | 0.75 | MAPT (0.38) | MEN1KMT2AMAPTPOLBMMP13 | |
| SCHEMBL18779843 | 0.74 | MAPT (0.37) | MEN1KMT2AMAPTPOLBMMP13 | |
| SCHEMBL9811268 | 0.72 | CDC25A (0.41) | MEN1KMT2ALMNA | |
| SCHEMBL28522891 | 0.71 | MAPT (0.37) | MEN1KMT2AMAPTPOLBMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607431-B1 | Cyanine dye compounds | LIFE TECHNOLOGIES CORP (US) | 2016-08-24 | — | — | EP | disclosed |
| EP-1720944-B1 | CYANINE DYE COMPOUNDS | LIFE TECHNOLOGIES CORP (US) | 2013-07-17 | — | — | EP | disclosed |
| EP-2607431-A1 | Cyanine dye compounds | Life Technologies Corporation (US) | 2013-06-26 | — | — | EP | disclosed |
| US-7842811-B2 | Cyanine dye compounds | Life Technologies Corporation (US) | 2010-11-30 | — | — | US | disclosed |
| US-20100120051-A1 | CYANINE DYE COMPOUNDS | Life Technologies Corporation (US) | 2010-05-13 | — | — | US | disclosed |
| US-7655409-B2 | Have negatively charged substituent for fluorescent staining of DNA; used to distinguish DNA present in a sample from RNA | Life Technologies Corporation (US) | 2010-02-02 | — | — | US | disclosed |
| US-20090047683-A1 | CYANINE DYE COMPOUNDS | INVITROGEN CORPORATION (US) | 2009-02-19 | — | — | US | disclosed |
| US-7446202-B2 | Cyanine dye compounds | MOLECULAR PROBES, INC. (US) | 2008-11-04 | — | — | US | disclosed |
| EP-1720944-A2 | CYANINE DYE COMPOUNDS | Molecular Probes Inc. (US) | 2006-11-15 | — | — | EP | disclosed |
| US-20050214810-A1 | Cyanine dye compounds | MOLECULAR PROBES, INC. | 2005-09-29 | — | — | US | disclosed |
| WO-2005056689-A2 | CYANINE DYE COMPOUNDS | MOLECULAR PROBES, INC. (US) | 2005-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050214810-A1 | Cyanine dye compounds | POLL, XPA, DUT | MEN1 1617/4885KMT2A 1231/4885MAPT 2786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.