SCHEMBL332504

SCHEMBL332504

SC(S)(Cc1ccc(Cl)cc1)Cc1ccc(Cl)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 3/20 0.54
SLC6A2 P23975 2/20 0.54
SLC6A3 Q01959 2/20 0.54
HTR2A P28223 1/20 0.54
HRH1 P35367 1/20 0.54
HTR2B P41595 1/20 0.54
CHRNA4 P43681 1/20 0.54
IDO1 P14902 4/20 0.52
TAAR1 Q96RJ0 2/20 0.42
LMNA P02545 2/20 0.42
CYP2A6 P11509 1/20 0.42
AGXT P21549 2/20 0.41
ALDH1A1 P00352 3/20 0.39
MAPT P10636 1/20 0.39
KCNH2 Q12809 1/20 0.39
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
CYP3A4 P08684 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3011129 0.80 SLC6A4 (0.61) SLC6A4SLC6A2SLC6A3HTR2AHRH1
SCHEMBL14040447 0.77 SLC6A4 (0.69) SLC6A4SLC6A2SLC6A3HTR2AHRH1
SCHEMBL3658885 0.76 SLC6A4 (0.56) SLC6A4SLC6A2SLC6A3HTR2AHRH1
SCHEMBL28848601 0.74 SLC6A4 (0.67) SLC6A4SLC6A2SLC6A3HTR2AHRH1
SCHEMBL73498 0.74 SLC6A4 (0.67) SLC6A4SLC6A2SLC6A3HTR2AHRH1
SCHEMBL462327 0.74 SLC6A4 (0.54) SLC6A4SLC6A2SLC6A3HTR2AHRH1
SCHEMBL331052 0.72 SLC6A2 (0.50) SLC6A2IDO1TAAR1LMNAALDH1A1
SCHEMBL11141219 0.72 SLC6A4 (0.52) SLC6A4SLC6A2SLC6A3HTR2AHRH1
SCHEMBL14935121 0.70 SLC6A4 (0.50) SLC6A4SLC6A2SLC6A3HTR2AHRH1
SCHEMBL9184761 0.70 CYP19A1 (0.58) SLC6A4SLC6A2SLC6A3HTR2AHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3483219-B1 TRANSPARENT PLASTIC SUBSTRATE AND PLASTIC LENS HOYA LENS THAILAND LTD (TH) 2024-08-14 EP disclosed
US-12054568-B2 Optical material composition and optical material TOKUYAMA CORPORATION (JP) 2024-08-06 US disclosed
EP-3643735-B1 PHOTOCHROMIC POLYROTAXANE COMPOUND, AND CURABLE COMPOSITION CONTAINING SAID PHOTOCHROMIC POLYROTAXANE COMPOUND TOKUYAMA CORP (JP) 2024-07-31 EP disclosed
CN-110869355-B Benzopyran compound, curable composition containing the compound, and optical article containing cured product formed from the curable composition 株式会社德山 2023-11-14 CN disclosed
CN-112424260-B Photochromic compound and curable composition containing the same 株式会社德山 2023-10-13 CN disclosed
US-11767467-B2 Photochromic compound and curable composition containing said photochromic compound TOKUYAMA CORPORATION (JP) 2023-09-26 US disclosed
CN-116438214-A Sealing material for organic EL display element, cured product thereof, and organic EL display device 三井化学株式会社 2023-07-14 CN disclosed
EP-3345954-B1 POLYROTAXANE, PRODUCTION METHOD THEREFOR, AND OPTICAL COMPOSITION CONTAINING SAID POLYROTAXANE TOKUYAMA CORP (JP) 2023-07-05 EP disclosed
CN-113045885-B Transparent plastic substrate and plastic lens 豪雅镜片泰国有限公司 2023-03-21 CN disclosed
EP-3653615-B1 CHROMENE COMPOUND, CURABLE COMPOSITION COMPRISING SAME, AND OPTICAL ARTICLE COMPRISING CURED PRODUCT FORMED OF CURABLE COMPOSITION TOKUYAMA CORP (JP) 2023-03-01 EP disclosed
US-5194559-A Reacting compounds containing isocyanate and isothiocyanate groups with polyol and polythiol; colorlrss, transparent MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-16 US disclosed
EP-0506315-A2 Optical urethane resins and plastic lenses comprising the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-30 EP disclosed
US-5126388-A Sulfur-containing polyurethane or polythiourethane and internal mold release agent MITSUI TOATSU CHEMICALS, INC. (JP) 1992-06-30 US disclosed
US-5059673-A bis(isocyanatomethyl)-norbornane or -4,7methonohexahydroindan e high refractive index, lightweight, high impact MITSUI TOATSU CHEMICALS, INC. (JP) 1991-10-22 US disclosed
US-5021503-A Polythiourethanes from sulfur-containing aliphatic diisocyanates and polythiols or polyols; colorless MITSUI TOATSU CHEMICALS, INC. (JP) 1991-06-04 US disclosed
US-5013496-A Polyurethane or polythiourethane MITSUI TOATSU CHEMICALS, INC. (JP) 1991-05-07 US disclosed
EP-0422836-A2 Resin for urethane lenses, lenses comprising the resin, and a process for preparation of the resin and the lenses MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-04-17 EP disclosed
EP-0374258-A1 HIGH REFRACTIVE INDEX LENS AND METHOD FOR ITS PRODUCTION MITSUI CHEMICALS, INC. (JP) 1990-06-27 EP disclosed
EP-0330363-A2 Highly-refractive plastic lens and process for making the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-30 EP disclosed
EP-0329387-A2 Plastic lens, and method for its preparation MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed