Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7670360 | 0.86 | ESR1 (0.38) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL4108567 | 0.79 | CA1 (0.38) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL29299426 | 0.78 | SLC6A4 (0.48) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL11515369 | 0.77 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL10570 | 0.76 | ALDH1A1 (0.52) | TAAR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3658885 | 0.76 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL10248786 | 0.76 | IDO1 (0.48) | IDO1TAAR1LMNAAGXT | |
| SCHEMBL11059680 | 0.75 | TAAR1 (0.50) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL16959914 | 0.75 | PIK3CA (0.41) | SLC6A4SLC6A3IDO1TAAR1GAA | |
| SCHEMBL25471464 | 0.74 | TRPA1 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112676307-A | Method for reducing and recycling catalyst residues | 江苏优普生物化学科技股份有限公司 | 2021-04-20 | — | — | CN | claimed |
| CN-114181074-A | Preparation method of p-chlorobenzoyl fluoride | 大连奇凯医药科技有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-113710788-A | Solvent composition and use thereof | 株式会社金子化学 | 2021-11-26 | — | — | CN | disclosed |
| CN-113661203-A | Acrylic modified polymeric sunscreen agents for use in organic media | 阿科玛股份有限公司 | 2021-11-16 | — | — | CN | disclosed |
| US-20210147408-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | BRISTOL MYERS SQUIBB CO (US) | 2021-05-20 | — | — | US | disclosed |
| US-20210147408-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | BRISTOL MYERS SQUIBB CO (US) | 2021-05-20 | — | — | US | disclosed |
| CN-112676307-A | Method for reducing and recycling catalyst residues | 江苏优普生物化学科技股份有限公司 | 2021-04-20 | — | — | CN | disclosed |
| CN-112624906-A | P-trifluoromethylaniline rectification kettle residue treatment process | 江苏优普生物化学科技股份有限公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-108349883-B | Method for synthesizing 2-alkyl-4-trifluoromethyl-3-alkylsulfonylbenzoic acid | 拜耳作物科学股份公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-107636038-B | Reactive compositions containing mercapto-functional silicon compounds | 莫门蒂夫性能材料股份有限公司 | 2020-09-22 | — | — | CN | disclosed |
| CN-107311873-B | Method for preparing 2, 6-dichloro-4-trifluoromethylaniline with 99% content | LIANYUNGANG AVILIVE CHEMICAL CO., LTD. (CN) | 2019-12-10 | — | — | CN | disclosed |
| WO-2019067702-A9 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-04-25 | — | — | WO | disclosed |
| WO-2019067702-A9 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-04-25 | — | — | WO | disclosed |
| WO-2019067702-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-04-04 | — | — | WO | disclosed |
| WO-2019067702-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-04-04 | — | — | WO | disclosed |
| WO-2015095788-A1 | 2-ACYLAMIDOMETHYL AND SULFONYLAMIDOMETHYL BENZOXAZINE CARBAMATES FOR INHIBITION OF RORgamma ACTIVITY AND THE TREATMENT OF DISEASE | MERCK SHARP & DOHME CORP. (US) | 2015-06-25 | — | — | WO | disclosed |
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| US-6034086-A | VIRICIDES; AIDS THERAPY | UBE INDUSTRIES, LTD. | 2000-03-07 | — | — | US | disclosed |
| EP-0206951-B1 | PROCESS FOR THE PERFLUOROALKYLATION OF AROMATIC DERIVATIVES | RHONE-POULENC CHIMIE (FR) | 1990-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147408-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | LGALS3, LGALS1, LGALS3BP | SLC6A4 4385/4885SLC6A2 4224/4885SLC6A3 2017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.