⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL557813 | 0.97 | — | — | |
| Bromide SCHEMBL556812 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL3510080 | 0.95 | DAO (0.40) | — | |
| SCHEMBL29291881 | 0.93 | TSHR (0.39) | — | |
| SCHEMBL27970306 | 0.91 | DAO (0.38) | — | |
| SCHEMBL5713341 | 0.86 | DAO (0.50) | — | |
| SCHEMBL796651 | 0.85 | — | — | |
| Bromide SCHEMBL556174 | 0.83 | TLR8 (0.44) | — | |
| SCHEMBL45207 | 0.83 | TLR8 (0.44) | — | |
| Hydrochloric Acid SCHEMBL6736377 | 0.83 | TLR8 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 552 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116239577-A | Method for preparing cudexestat | 沈阳药科大学 | 2023-06-09 | — | — | CN | claimed |
| US-20230052747-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF TUMORS | TES PHARMA S.R.L. (IT) | 2023-02-16 | — | — | US | claimed |
| CN-109456200-B | Preparation method of m-xylylenediamine | 万华化学集团股份有限公司 | 2021-07-23 | — | — | CN | claimed |
| EP-3809876-A1 | PROTECTIVE AGENT FOR FOOD PRODUCTS AND THE LIKE AND FOR CURING AND/OR STORAGE ROOMS OF THE SAME | PERPRIN S.R.L. (IT) | 2021-04-28 | — | — | EP | claimed |
| CN-112294965-A | Pharmaceutical compositions of MDM2 inhibitors and their use in the prevention and/or treatment of diseases | 苏州亚盛药业有限公司 | 2021-02-02 | — | — | CN | claimed |
| US-10772874-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. | 2020-09-15 | — | — | US | claimed |
| CN-111138713-A | Stearylamine modified ammonium polyphosphate and preparation method and application thereof | 上海普利特复合材料股份有限公司 | 2020-05-12 | — | — | CN | claimed |
| WO-2019243869-A1 | PROTECTIVE AGENT FOR FOOD PRODUCTS AND THE LIKE AND FOR CURING AND/OR STORAGE ROOMS OF THE SAME | PERPRIN S.R.L. (IT) | 2019-12-26 | — | — | WO | claimed |
| US-10456382-B2 | Compounds and compositions for the inhibition of NAMPT | FORMA TM, LLC (US) | 2019-10-29 | — | — | US | claimed |
| US-20190105307-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | Valo Health, LLC | 2019-04-11 | — | — | US | claimed |
| EP-2611804-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | Forma TM, LLC. (US) | 2013-07-10 | — | — | EP | claimed |
| WO-2012031197-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | FORMA THERAPEUTICS, INC. (US) | 2012-03-08 | — | — | WO | claimed |
| US-20100035855-A1 | Method for treating or preventing a cardiovascular disease or condition utilizing estrogen receptor modulators based on APOE allelic profile of a mammalian subject | SEARETE LLC, A LIMITED LIABILITY CORPORATION OF THE STATE OF DELAWARE | 2010-02-11 | — | — | US | claimed |
| US-7601871-B2 | Ion exchanging; ionic liquids | HONEYWELL INTERNATIONAL INC. (US) | 2009-10-13 | — | — | US | claimed |
| US-20060247472-A1 | Method for purifying quaternary onium salts | HONEYWELL INTERNATIONAL INC. (US) | 2006-11-02 | — | — | US | claimed |
| WO-2002012161-A1 | PROCESS FOR THE CARBONYLATION OF OXIRANES | DAVY PROCESS TECHNOLOGY LIMITED (GB) | 2002-02-14 | — | — | WO | claimed |
| EP-0676429-B1 | Composition for urethane-based plastic lens | MITSUI CHEMICALS INC (JP) | 2000-12-27 | — | — | EP | claimed |
| US-RE33907-E | Anti-spasmodic agents having a heterocyclic ring | UNITED PHARMACEUTICALS, INC. (US) | 1992-04-28 | — | — | US | claimed |
| US-4857535-A | THIOESTERS | UNITED PHARMACEUTICALS (US) | 1989-08-15 | — | — | US | claimed |
| US-4721783-A | SMOOTH MUSCLES | UNITED PHARMACEUTICALS, INC. (US) | 1988-01-26 | — | — | US | claimed |