Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6114513 | 0.98 | TBXAS1 (0.47) | TLR8TLR7TBXAS1NOS1DAO | |
| SCHEMBL5691507 | 0.98 | TBXAS1 (0.47) | TLR8TLR7TBXAS1NOS1DAO | |
| SCHEMBL11438392 | 0.98 | TBXAS1 (0.47) | TLR8TLR7TBXAS1NOS1DAO | |
| SCHEMBL11440961 | 0.98 | TBXAS1 (0.47) | TLR8TLR7TBXAS1NOS1DAO | |
| SCHEMBL6114991 | 0.98 | TBXAS1 (0.47) | TLR8TLR7TBXAS1NOS1DAO | |
| SCHEMBL6114927 | 0.98 | TBXAS1 (0.47) | TLR8TLR7TBXAS1NOS1DAO | |
| Hydrochloric Acid SCHEMBL31520475 | 0.98 | TLR8 (0.43) | TLR8TLR7TBXAS1NOS1DAO | |
| SCHEMBL6114640 | 0.98 | TBXAS1 (0.47) | TLR8TLR7TBXAS1NOS1DAO | |
| SCHEMBL6114716 | 0.98 | TBXAS1 (0.47) | TLR8TLR7TBXAS1NOS1DAO | |
| SCHEMBL11775156 | 0.98 | TBXAS1 (0.47) | TLR8TLR7TBXAS1NOS1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3141 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028582-B | Preparation method of N-aryl pyrazole medicine E-52862 and product thereof | 曲靖师范学院 | 2024-04-12 | — | — | CN | claimed |
| CN-117777024-A | Improved process for preparing arylpyrazole nitriles | 江苏优普生物化学科技股份有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-114456117-B | Iodine-promoted method for preparing N-aryl pyrazole compound | 曲靖师范学院 | 2023-12-26 | — | — | CN | claimed |
| CN-117024403-A | Phenylpyrazole compound and application thereof | 沈阳化工大学 | 2023-11-10 | — | — | CN | claimed |
| CN-114181152-B | Preparation method of arylpyrazole drug intermediate | 中国农业科学院兰州畜牧与兽药研究所 | 2023-08-22 | — | — | CN | claimed |
| CN-114213329-B | Preparation method of aryl pyrazole compound | 中国农业科学院兰州畜牧与兽药研究所 | 2023-08-22 | — | — | CN | claimed |
| CN-115850336-A | Aryl-pyrazole axis chiral compound and preparation method and application thereof | 四川大学 | 2023-03-28 | — | — | CN | claimed |
| CN-115819348-A | Process for preparing N-arylpyrazole compound | 曲靖师范学院 | 2023-03-21 | — | — | CN | claimed |
| CN-115677588-A | 2,3,5,5-tetrasubstituted-4-carbonyl imidazole cyclic nitrone compound, preparation method and application | 中国科学院成都有机化学有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-115572258-A | C 2 Preparation method of axial chiral biquinoline framework compound | 中国科学院成都有机化学有限公司 | 2023-01-06 | — | — | CN | claimed |
| EP-0226156-A2 | 1-Aryl-pyrazoles | BAYER AG (DE) | 1987-06-24 | — | — | EP | claimed |
| EP-0224094-A2 | 1-Aryl-pyrazole | BAYER AG (DE) | 1987-06-03 | — | — | EP | claimed |
| EP-0222253-A1 | Substituted 5-amino-1-aryl-pyrazoles | BAYER AG (DE) | 1987-05-20 | — | — | EP | claimed |
| EP-0216102-A1 | 1-Arylpyrazoles | BAYER AG (DE) | 1987-04-01 | — | — | EP | claimed |
| EP-0212354-A2 | 1-Aryl pyrazoles | BAYER AG (DE) | 1987-03-04 | — | — | EP | claimed |
| CN-86105140-A | The 1-aryl pyrazole compound | — | 1987-02-25 | — | — | CN | claimed |
| EP-0116121-B1 | PROCESS FOR THE PHOTOPOLYMERIZATION OF VINYL COMPOUNDS AND PHOTOPOLYMERIZED MATERIAL | Kulzer & Co. GmbH (DE) | 1986-10-22 | — | — | EP | claimed |
| EP-0191282-A1 | 1-Aryl-4-nitropyrazoles | BAYER AG (DE) | 1986-08-20 | — | — | EP | claimed |
| EP-0116121-A1 | Process for the photopolymerization of vinyl compounds and photopolymerized material | Kulzer & Co. GmbH (DE) | 1984-08-22 | — | — | EP | claimed |
| EP-0022078-B1 | PYRAZOLO-QUINOLINES, PROCESSES FOR THEIR PRODUCTION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1984-07-25 | — | — | EP | claimed |