⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3691794 | 0.69 | — | — | |
| SCHEMBL18730252 | 0.67 | — | — | |
| SCHEMBL15607634 | 0.65 | — | — | |
| SCHEMBL13347877 | 0.65 | — | — | |
| SCHEMBL12439267 | 0.65 | — | — | |
| SCHEMBL7810330 | 0.65 | — | — | |
| SCHEMBL3172880 | 0.65 | — | — | |
| SCHEMBL15108915 | 0.65 | — | — | |
| SCHEMBL961759 | 0.65 | — | — | |
| SCHEMBL15121080 | 0.63 | ALPL (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110088101-A | A kind of nitrogen-containing hetero cyclics, preparation method, pharmaceutical composition and application | 罗欣药业(上海)有限公司 | 2019-08-02 | — | — | CN | disclosed |
| US-20150335021-A1 | Cycloclavine and Derivatives Thereof for Controlling Invertebrate Pests | BASF SE (DE) | 2015-11-26 | — | — | US | disclosed |
| US-8999889-B2 | Substituted ketonic isoxazoline compounds and derivatives for combating animal pests | BASF SE (DE) | 2015-04-07 | — | — | US | disclosed |
| EP-2114941-B1 | BICYCLIC HETEROCYCLIC COMPOUNDS AS FGFR INHIBITORS | ASTEX THERAPEUTICS LTD (GB) | 2015-03-25 | — | — | EP | disclosed |
| EP-2114941-B1 | BICYCLIC HETEROCYCLIC COMPOUNDS AS FGFR INHIBITORS | ASTEX THERAPEUTICS LTD (GB) | 2015-03-25 | — | — | EP | disclosed |
| US-8895745-B2 | Bicyclic heterocyclic compounds as FGFR inhibitors | ASTEX THERAPEUTICS LIMITED (GB) | 2014-11-25 | — | — | US | disclosed |
| US-8895745-B2 | Bicyclic heterocyclic compounds as FGFR inhibitors | ASTEX THERAPEUTICS LIMITED (GB) | 2014-11-25 | — | — | US | disclosed |
| US-8722673-B2 | Imine compounds for combating invertebrate pests | BASF SE (DE) | 2014-05-13 | — | — | US | disclosed |
| US-8653000-B2 | Imine substituted 2,4-diaryl-pyrroline derivatives as pesticides | BASF SE (DE) | 2014-02-18 | — | — | US | disclosed |
| US-8633134-B2 | Substituted amidine compounds for combating animal pests | BASF SE (DE) | 2014-01-21 | — | — | US | disclosed |
| US-20110257011-A1 | Substituted Amidine Compounds for Combating Animal Pests | BASF SE (US) | 2011-10-20 | — | — | US | disclosed |
| US-20100120761-A1 | Bicyclic Heterocyclic Compounds as FGFR Inhibitors | ASTEX THERAPEUTICS LIMITED (GB) | 2010-05-13 | — | — | US | disclosed |
| US-20100120761-A1 | Bicyclic Heterocyclic Compounds as FGFR Inhibitors | ASTEX THERAPEUTICS LIMITED (GB) | 2010-05-13 | — | — | US | disclosed |
| EP-2114941-A1 | BICYCLIC HETEROCYCLIC COMPOUNDS AS FGFR INHIBITORS | Astex Therapeutics Limited (GB) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008078091-A1 | BICYCLIC HETEROCYCLIC COMPOUNDS AS FGFR INHIBITORS | ASTEX THERAPEUTICS LIMITED (GB) | 2008-07-03 | — | — | WO | disclosed |
| WO-2008078091-A1 | BICYCLIC HETEROCYCLIC COMPOUNDS AS FGFR INHIBITORS | ASTEX THERAPEUTICS LIMITED (GB) | 2008-07-03 | — | — | WO | disclosed |
| EP-0208281-B1 | QUINOLINE 8-CARBOXYLIC-ACID AZOLIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1991-01-30 | — | — | EP | disclosed |
| US-4832731-A | Quinoline-8-carboxylic acid azolides and their use as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1989-05-23 | — | — | US | disclosed |
| EP-0208281-A2 | Quinoline 8-carboxylic-acid azolides, process for their preparation and their use as herbicides | BASF Aktiengesellschaft (DE) | 1987-01-14 | — | — | EP | disclosed |
| EP-0025859-A2 | Process for the synthesis of 1,2,4-triazoles | BASF Aktiengesellschaft (DE) | 1981-04-01 | — | — | EP | disclosed |