Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 5/20 | 0.40 |
| ▸ | MAOA | P21397 | 12/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4955298 | 0.96 | CALML3 (0.43) | CALML3MAOAMAOB | |
| SCHEMBL13298921 | 0.94 | MIF (0.38) | CALML3MAOAMAOBMIF | |
| SCHEMBL3323967 | 0.90 | CALML3 (0.40) | CALML3MAOAMAOB | |
| SCHEMBL3331952 | 0.88 | CALML3 (0.50) | CALML3MAOAMAOB | |
| SCHEMBL3328449 | 0.85 | CALML3 (0.53) | CALML3MAOAMAOB | |
| SCHEMBL3331210 | 0.85 | CALML3 (0.53) | CALML3MAOAMAOB | |
| SCHEMBL13298916 | 0.85 | CALML3 (0.45) | CALML3MAOAMAOBMIF | |
| SCHEMBL3328394 | 0.81 | MAOA (0.54) | CALML3MAOAMAOB | |
| SCHEMBL4954193 | 0.81 | CALML3 (0.47) | CALML3MAOAMAOB | |
| SCHEMBL4954187 | 0.81 | CALML3 (0.47) | CALML3MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137243-A1 | Oxazolidinone And/Or Isoxazoline As Antibacterial Agents | ASTRAZENECA AB (SE) | 2010-06-03 | — | — | US | disclosed |
| EP-1427711-B1 | OXAZOLIDINONE AND/OR ISOXAZOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2005-07-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137243-A1 | Oxazolidinone And/Or Isoxazoline As Antibacterial Agents | CYP8B1, HRH2, CYP2W1 | CALML3 4624/4885MAOA 482/4885MAOB 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.