SCHEMBL33272

SCHEMBL33272

Cc1nc2cc(C)c(C)cc2s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 1.00
SMN1; SMN2 Q16637 7/20 0.74
ALDH1A1 P00352 4/20 0.74
TP53 P04637 3/20 0.74
NPC1 O15118 2/20 0.74
RAB9A P51151 2/20 0.74
HSD17B10 Q99714 2/20 0.74
PKM P14618 2/20 0.74
MAPT P10636 1/20 0.74
HPGD P15428 1/20 0.74
CYP3A4 P08684 1/20 0.63
TSHR P16473 1/20 0.63
ALOX15 P16050 1/20 0.49
ATM Q13315 1/20 0.49
CHRNB2 P17787 1/20 0.47
CHRNA4 P43681 1/20 0.47
HTT P42858 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.44
KMT2A Q03164 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30422583 1.00 GAA (1.00) GAASMN1; SMN2ALDH1A1TP53NPC1
Bromide SCHEMBL10995945 0.98 GAA (0.95) GAASMN1; SMN2ALDH1A1TP53NPC1
SCHEMBL4384430 0.87 SMN1; SMN2 (0.85) GAASMN1; SMN2ALDH1A1TP53NPC1
SCHEMBL12635465 0.85 SMN1; SMN2 (1.00) GAASMN1; SMN2ALDH1A1TP53NPC1
SCHEMBL617940 0.83 GAA (0.70) GAASMN1; SMN2ALDH1A1TP53NPC1
SCHEMBL17561698 0.83 GAA (0.70) GAASMN1; SMN2ALDH1A1TP53NPC1
SCHEMBL17561699 0.83 GAA (0.70) GAASMN1; SMN2ALDH1A1TP53NPC1
SCHEMBL2088758 0.83 GAA (0.70) GAASMN1; SMN2ALDH1A1TP53NPC1
SCHEMBL21606916 0.83 GAA (0.70) GAASMN1; SMN2ALDH1A1TP53NPC1
SCHEMBL8977888 0.83 GAA (0.70) GAASMN1; SMN2ALDH1A1TP53NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US claimed
CN-118355041-A Method for underwater bonding 汉高股份有限及两合公司 2024-07-16 CN claimed
CN-118048155-A Titanium nitride etching liquid, preparation method, application and cleaning method thereof 浙江奥首材料科技有限公司 2024-05-17 CN claimed
CN-113045993-A Polishing solution for processing ultra-smooth low-damage bearing steel surface and application thereof 西南交通大学 2021-06-29 CN claimed
EP-3464446-B1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2021-06-23 EP claimed
CN-109476874-B Two-part cyanoacrylate curable adhesive systems 汉高知识产权控股有限责任公司 2021-04-16 CN claimed
US-10655015-B2 Tire crumb-based bitumen polymer for producing a lower viscosity asphalt with improved tolerance to high temperatures Argopro Group LLC (US) 2020-05-19 US claimed
US-20200095424-A1 TIRE CRUMB-BASED BITUMEN POLYMER FOR PRODUCING A LOWER VISCOSITY ASPHALT WITH IMPROVED TOLERANCE TO HIGH TEMPERATURES Argopro Group LLC 2020-03-26 US claimed
CN-109729960-A Landscape combined type rainwater comprehensive utilization equipment 徐州工程学院 2019-05-10 CN claimed
EP-3464446-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2019-04-10 EP claimed
US-10100235-B2 Two-part cyanoacrylate curable adhesive system Henkel IP & Holding GmbH (DE) 2018-10-16 US claimed
WO-2017202698-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2017-11-30 WO claimed
US-20170335151-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM HENKEL AG & CO. KGAA (DE) 2017-11-23 US claimed
EP-2346956-A1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES Loctite (R & D) Limited (IE) 2011-07-27 EP claimed
WO-2010046412-A1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES LOCTITE (R & D) LIMITED (IE) 2010-04-29 WO claimed
US-4308390-A Process for the production of sulphoalkyl quaternary salts AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1981-12-29 US claimed
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US disclosed
CN-118355041-A Method for underwater bonding 汉高股份有限及两合公司 2024-07-16 CN disclosed
US-4308390-A Process for the production of sulphoalkyl quaternary salts AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1981-12-29 US disclosed
US-4287348-A BY REACTING A HYDROXYALKYLSULFONIC ACID WITH A NITROGEN-CONTAINING HETEROCYCLIC BASE CIBA-GEIGY AG (CH) 1981-09-01 US disclosed