SCHEMBL4384430

SCHEMBL4384430

Cc1nc2cc3sc(C)nc3cc2s1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.85
NPC1 O15118 4/20 0.85
RAB9A P51151 4/20 0.85
ALDH1A1 P00352 3/20 0.85
HSD17B10 Q99714 2/20 0.85
TP53 P04637 2/20 0.85
MAPT P10636 1/20 0.85
PKM P14618 1/20 0.85
HPGD P15428 1/20 0.85
GAA P10253 2/20 0.77
ALOX15 P16050 1/20 0.53
ATM Q13315 1/20 0.53
CHRNB2 P17787 1/20 0.52
CHRNA4 P43681 1/20 0.52
TDP1 Q9NUW8 2/20 0.50
MAPK1 P28482 1/20 0.50
HTT P42858 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.48
KMT2A Q03164 2/20 0.47
LDHA P00338 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12635465 0.92 SMN1; SMN2 (1.00) SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10
SCHEMBL33272 0.87 GAA (1.00) SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10
SCHEMBL30422583 0.87 GAA (1.00) SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10
SCHEMBL19757341 0.87 SMN1; SMN2 (0.72) SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10
SCHEMBL19250836 0.87 SMN1; SMN2 (0.65) SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10
Bromide SCHEMBL10995945 0.85 GAA (0.95) SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10
SCHEMBL14297419 0.84 SMN1; SMN2 (0.68) SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10
SCHEMBL1608822 0.84 SMN1; SMN2 (0.68) SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10
SCHEMBL30423025 0.84 SMN1; SMN2 (0.68) SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10
SCHEMBL8653076 0.84 SMN1; SMN2 (0.68) SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122060373-A Epoxy-based multifunctional protective coating with enhanced azole bridging two-dimensional organic framework, and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2026-05-19 CN disclosed
CN-119431703-A Preparation method and application of lithium anode based on benzothiazolyl covalent organic framework modification 南开大学 2025-02-14 CN disclosed
US-12043749-B2 Method for producing ink composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-07-23 US disclosed
US-12043749-B2 Method for producing ink composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-07-23 US disclosed
US-11917839-B2 High signal-to-noise ratio photoelectric conversion element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-02-27 US disclosed
US-11917839-B2 High signal-to-noise ratio photoelectric conversion element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-02-27 US disclosed
US-20240023422-A1 COMPOSITION, FILM, ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, AND PHOTODETECTION ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-01-18 US disclosed
US-20240023422-A1 COMPOSITION, FILM, ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, AND PHOTODETECTION ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-01-18 US disclosed
US-11877459-B2 Light detecting element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-01-16 US disclosed
US-11877459-B2 Light detecting element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-01-16 US disclosed
US-7504161-B2 Luminescent element FUJIFILM CORPORATION (JP) 2009-03-17 US disclosed
US-7504161-B2 Luminescent element FUJIFILM CORPORATION (JP) 2009-03-17 US disclosed
US-20080193700-A1 Metal Chelates and Their Use in Optical Recording Media Having High Storage Capacity CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2008-08-14 US disclosed
US-20080193700-A1 Metal Chelates and Their Use in Optical Recording Media Having High Storage Capacity CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2008-08-14 US disclosed
US-20080193700-A1 Metal Chelates and Their Use in Optical Recording Media Having High Storage Capacity CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2008-08-14 US disclosed
US-20070179299-A1 Dioxaborines as organic n-semiconductors, process for the production of semiconductors utilizing dioxaborines, and semiconductor component, field effect transistor, and diode having a dioxaborine INFINEON TECHNOLOGIES AG 2007-08-02 US disclosed
EP-1743333-A1 METAL CHELATES AND THEIR USE IN OPTICAL RECORDING MEDIA HAVING HIGH STORAGE CAPACITY CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2007-01-17 EP disclosed
US-20070004873-A1 Second order nonlinear optical polyimides having benzobisthiazole-based pendant groups, and preparation of the same NATIONAL SUN YAT-SEN UNIVERSITY 2007-01-04 US disclosed
US-20070001154-A1 Second order nonlinear optical polyimides having benzobisthiazole-based pendant groups, and preparation of the same NATIONAL SUN YAT-SEN UNIVERSITY 2007-01-04 US disclosed
WO-2005106868-A1 METAL CHELATES AND THEIR USE IN OPTICAL RECORDING MEDIA HAVING HIGH STORAGE CAPACITY CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-11-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080193700-A1 Metal Chelates and Their Use in Optical Recording Media Having High Storage Capacity TMCO1, KCNN3, CACNA1F SMN1; SMN2 893/4885NPC1 3103/4885RAB9A 1255/4885
US-20070179299-A1 Dioxaborines as organic n-semiconductors, process for the production of semiconductors utilizing dioxaborines, and semiconductor component, field effect transistor, and diode having a dioxaborine NME2, DDT, DBF4 SMN1; SMN2 2595/4885NPC1 2800/4885RAB9A 1014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.