⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13337061 | 1.00 | — | — | |
| SCHEMBL12122091 | 1.00 | — | — | |
| SCHEMBL12122090 | 0.77 | ALDH1A1 (0.34) | — | |
| SCHEMBL3326102 | 0.77 | ALDH1A1 (0.34) | — | |
| SCHEMBL12341104 | 0.77 | ALDH1A1 (0.34) | — | |
| SCHEMBL9452626 | 0.75 | — | — | |
| SCHEMBL14670011 | 0.74 | CPA1 (0.36) | — | |
| SCHEMBL265274 | 0.74 | — | — | |
| SCHEMBL10522453 | 0.73 | TSHR (0.34) | — | |
| SCHEMBL28413407 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338620-B2 | Methods for the production of C-8 lactam lactone compounds | NOVARTIS AG (CH) | 2012-12-25 | — | — | US | disclosed |
| US-20100130749-A1 | METHODS | NODEN PHARMA DAC (IE) | 2010-05-27 | — | — | US | disclosed |
| CN-101679213-A | New methods | NOVARTIS AG | 2010-03-24 | — | — | CN | disclosed |
| EP-2142497-A1 | NEW METHODS | Novartis Ag (CH) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008119804-A1 | NEW METHODS | NOVARTIS AG (CH) | 2008-10-09 | — | — | WO | disclosed |