Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28681291 | 1.00 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1TDP1MAPTKDM4E | |
| Benzene SCHEMBL28083527 | 0.96 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1TDP1MAPTKDM4E | |
| SCHEMBL453160 | 0.96 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1TDP1MAPTKDM4E | |
| SCHEMBL9490577 | 0.96 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1TDP1MAPTKDM4E | |
| SCHEMBL30959 | 0.96 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1TDP1MAPTKDM4E | |
| Methane SCHEMBL23501806 | 0.92 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1TDP1MAPTKDM4E | |
| SCHEMBL2389596 | 0.92 | ALDH1A1 (0.72) | ALDH1A1L3MBTL1TDP1MAPTKDM4E | |
| SCHEMBL3628751 | 0.92 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1TDP1MAPTKDM4E | |
| SCHEMBL8404848 | 0.92 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1TDP1MAPTKDM4E | |
| Ammonia Solution, Strong SCHEMBL20336769 | 0.92 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1TDP1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025033185-A1 | FLUX AND METHOD FOR PRODUCING JOINED BODY | 千住金属工業株式会社 | 2025-02-13 | — | — | WO | disclosed |
| CN-118561740-A | Liquid organic hydrogen storage compound and application thereof | 武汉氢阳能源有限公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-116396293-A | AIE type luminescent material and preparation method thereof | 扬州工业职业技术学院 | 2023-07-07 | — | — | CN | disclosed |
| CN-112812115-B | Acridine compound, polymer, application of polymer and light-emitting device | 广东聚华印刷显示技术有限公司 | 2022-03-29 | — | — | CN | disclosed |
| CN-109761879-B | Organic blue fluorescent material, preparation method thereof and organic electroluminescent device | 太原理工大学 | 2022-03-29 | — | — | CN | disclosed |
| CN-112812115-A | Acridine compound, polymer, application of polymer and light-emitting device | 广东聚华印刷显示技术有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-107739428-A | Side chain is poly- containing hole transporting unit（Fluorenes co S, S dioxydibenze bithiophenes）Derivative and its preparation method and application | 华南理工大学 | 2018-02-27 | — | — | CN | disclosed |
| CN-103476764-B | Process for producing episulfide compound | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2016-05-25 | — | — | CN | disclosed |
| US-9171676-B2 | Organic colourant and uses thereof in photovoltaic cells | COMMISSARIAT {dot over (A)} L'ĖNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (FR) | 2015-10-27 | — | — | US | disclosed |
| US-20140290748-A1 | ORGANIC COLOURANT AND USES THEREOF IN PHOTOVOLTAIC CELLS | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2014-10-02 | — | — | US | disclosed |
| US-8461282-B2 | (Pentaphenyl)phenyl group containing compound, polymeric derivative thereof and method for forming the same | NATIONAL TAIWAN UNIVERSITY (TW) | 2013-06-11 | — | — | US | disclosed |
| US-20100137461-A1 | (Pentaphenyl)phenyl Group Containing Compound, Polymeric Derivative Thereof And Method For Forming The Same | NATIONAL TAIWAN UNIVERSITY (TW) | 2010-06-03 | — | — | US | disclosed |
| US-20080293945-A1 | (Pentaphenyl)phenyl Group Containing Compound, Polymeric Derivative Thereof And Method For Forming The Same | NATIONAL TAIWAN UNIVERSITY (TW) | 2008-11-27 | — | — | US | disclosed |
| CN-1314656-C | 9,9-bis(triphenyl amino) fluorine derivatives and preparation and use thereof | SHANGHAI INST ORGANIC CHEM (CN) | 2007-05-09 | — | — | CN | disclosed |
| CN-1634864-A | 9,9-bis(triphenyl amino) fluorine derivatives and preparation and use thereof | SHANGHAI INST ORGANIC CHEM (CN) | 2005-07-06 | — | — | CN | disclosed |
| US-4201721-A | A PHENOL AND CARBON MONOXIDE WITH OXIDANT USING PLATINUM GROUP CATALYST | GENERAL ELECTRIC COMPANY (US) | 1980-05-06 | — | — | US | disclosed |