Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.48 |
| ▸ | PRKCA | P17252 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9479699 | 1.00 | NAAA (0.48) | NAAAPRKCASMN1; SMN2GNAI3GNAO1 | |
| SCHEMBL28986889 | 0.99 | NAAA (0.46) | NAAAPRKCASMN1; SMN2GNAI3GNAO1 | |
| SCHEMBL28986887 | 0.95 | NAAA (0.40) | NAAAPRKCASMN1; SMN2 | |
| SCHEMBL3459903 | 0.95 | SMN1; SMN2 (0.41) | NAAAPRKCASMN1; SMN2 | |
| SCHEMBL29029463 | 0.93 | NAAA (0.42) | NAAADGKA | |
| SCHEMBL8008803 | 0.90 | SMN1; SMN2 (0.38) | NAAAPRKCASMN1; SMN2 | |
| SCHEMBL7760256 | 0.88 | SMN1; SMN2 (0.39) | NAAASMN1; SMN2 | |
| SCHEMBL29093548 | 0.83 | NAAA (0.37) | NAAAPRKCASMN1; SMN2 | |
| SCHEMBL29192592 | 0.81 | SMN1; SMN2 (0.33) | NAAAPRKCASMN1; SMN2 | |
| SCHEMBL29106464 | 0.78 | NAAA (0.47) | NAAAPRKCADGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100136004-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISORDERS | MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC. | 2010-06-03 | — | — | US | disclosed |
| WO-2008148023-A2 | COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISORDERS | MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC. (US) | 2008-12-04 | — | — | WO | disclosed |