Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1LG2 | Q9BQ51 | 8/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 8/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3842800 | 0.90 | PDCD1LG2 (0.36) | PDCD1LG2CD274MEP1BALOX5APFEN1 | |
| SCHEMBL29423657 | 0.87 | KDM4E (0.40) | S1PR4NQO2KDM4EPKMRCE1 | |
| SCHEMBL3329129 | 0.87 | ABL1 (0.37) | S1PR4NQO2KDM4EPKMRCE1 | |
| SCHEMBL115368 | 0.87 | KDM4E (0.40) | S1PR4NQO2KDM4EPKMRCE1 | |
| SCHEMBL29442558 | 0.87 | KDM4E (0.40) | S1PR4NQO2KDM4EPKMRCE1 | |
| SCHEMBL3327356 | 0.86 | NQO2 (0.35) | S1PR4NQO2KDM4EPKMRCE1 | |
| SCHEMBL3328865 | 0.85 | ALOX5AP (0.46) | NQO2KDM4EPKMRCE1ALDH1A1 | |
| SCHEMBL3328556 | 0.84 | KDM4E (0.38) | S1PR4NQO2KDM4EPKMRCE1 | |
| SCHEMBL16047078 | 0.84 | KDM4E (0.39) | NQO2KDM4EPKMRCE1ALDH1A1 | |
| SCHEMBL2467010 | 0.83 | CD274 (0.41) | PDCD1LG2CD274MEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962523-B2 | Herbicide/safener combination | BAYER CROPSCIENCE AG (DE) | 2015-02-24 | — | — | US | disclosed |
| US-20150051074-A1 | HERBICIDE/SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2015-02-19 | — | — | US | disclosed |
| US-20100137137-A1 | HERBICIDE/SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137137-A1 | HERBICIDE/SAFENER COMBINATION | DDT, CYP2W1, GAP43 | PDCD1LG2 2223/4885CD274 3162/4885S1PR4 4235/4885 |
| US-20150051074-A1 | HERBICIDE/SAFENER COMBINATION | DDT, CYP2W1, GAP43 | PDCD1LG2 2223/4885CD274 3162/4885S1PR4 4235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.