SCHEMBL115368

SCHEMBL115368

COC(=O)c1nc(-c2ccc(Cl)c(OC)c2F)cc(N)c1Cl

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.40
PKM P14618 2/20 0.40
RCE1 Q9Y256 1/20 0.40
ALPL P05186 2/20 0.39
NQO2 P16083 2/20 0.38
MEP1B Q16820 1/20 0.37
GAA P10253 1/20 0.36
ABL1 P00519 1/20 0.35
ALDH1A1 P00352 4/20 0.34
TAS1R3 Q7RTX0 2/20 0.34
TAS1R1 Q7RTX1 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TAS1R2 Q8TE23 1/20 0.34
S1PR4 O95977 1/20 0.34
SCN10A Q9Y5Y9 1/20 0.34
HSP90AA1 P07900 2/20 0.33
HSP90AB1 P08238 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29442558 1.00 KDM4E (0.40) KDM4EPKMRCE1ALPLNQO2
SCHEMBL29423657 1.00 KDM4E (0.40) KDM4EPKMRCE1ALPLNQO2
SCHEMBL24066901 0.93 MEP1B (0.34) KDM4EPKMRCE1ALPLNQO2
SCHEMBL16047078 0.92 KDM4E (0.39) KDM4EPKMRCE1ALPLNQO2
SCHEMBL14354231 0.92 KDM4E (0.40) KDM4EPKMRCE1ALPLNQO2
SCHEMBL30481033 0.92 ALPL (0.43) KDM4EPKMRCE1ALPLNQO2
SCHEMBL3326424 0.92 ALPL (0.43) KDM4EPKMRCE1ALPLNQO2
SCHEMBL3329129 0.91 ABL1 (0.37) KDM4EPKMRCE1ALPLNQO2
SCHEMBL15128619 0.91 KDM4E (0.40) KDM4EPKMRCE1ALPLNQO2
SCHEMBL15795767 0.90 MEP1B (0.34) KDM4EPKMRCE1ALPLNQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1969 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116634870-A Herbicidal combinations 安道麦阿甘有限公司 2023-08-22 CN claimed
US-20230047569-A1 PESTICIDAL COMPLEX COMPOSITIONS FOR SYNERGISTIC DELIVERY OF PESTICIDAL ACTIVE INGREDIENTS AND METHODS OF SELECTION THEREOF 0903608 B.C. LTD. (CA) 2023-02-16 US claimed
US-20230000081-A1 SYNERGISTIC PESTICIDAL COMPOSITIONS FOR DELIVERY OF PESTICIDAL ACTIVE INGREDIENTS AND METHODS THEREFOR 0903608 B.C. LTD. (CA) 2023-01-05 US claimed
US-20220039384-A1 SELECTIVE WEED CONTROL WITH HALAUXIFEN OR 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR DERIVATIVES THEREOF IN VINEYARDS OR PERENNIAL CROPS CORTEVA AGRISCIENCE LLC (US) 2022-02-10 US claimed
US-11185072-B2 Selective weed control with halauxifen or 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl) pyridine-2-carboxylic acid or derivatives thereof in vineyards or perennial crops CORTEVA AGRISCIENCE LLC (US) 2021-11-30 US claimed
US-20210352895-A1 SYNERGISTIC PESTICIDAL COMPOSITIONS AND METHODS FOR DELIVERY OF ACTIVE INGREDIENTS 0903608 B.C. LTD. (CA) 2021-11-18 US claimed
EP-3855909-A1 SYNERGISTIC PESTICIDAL COMPOSITIONS FOR DELIVERY OF PESTICIDAL ACTIVE INGREDIENTS AND METHODS THEREFOR 0903608 B.C. Ltd. (CA) 2021-08-04 EP claimed
EP-3855910-A1 SYNERGISTIC PESTICIDAL COMPOSITIONS AND METHODS FOR DELIVERY OF ACTIVE INGREDIENTS 0903608 B.C. Ltd. (CA) 2021-08-04 EP claimed
CN-113163763-A Synergistic pesticidal compositions and methods for delivering active ingredients 0903608BC有限公司 2021-07-23 CN claimed
CN-113163762-A Synergistic pesticidal compositions for delivery of pesticidal active ingredients and methods thereof 0903608BC有限公司 2021-07-23 CN claimed
WO-2010146031-A2 FUNGICIDAL MIXTURES BASF SE (DE) 2010-12-23 WO claimed
US-20100322990-A1 METHODS FOR CONTROLLING PESTS BASF CORPORATION (US) 2010-12-23 US claimed
WO-2010139653-A1 FUNGICIDAL MIXTURES COMPRISING HETERAROMATIC SULFONAMIDES BASF SE (DE) 2010-12-09 WO claimed
US-20100311588-A1 SYNERGISTIC HERBICIDAL COMBINATIONS COMPRISING TEMBOTRIONE BAYER CROPSCIENCE AG (DE) 2010-12-09 US claimed
US-20100304973-A1 HERBICIDAL COMBINATIONS COMPRISING TEFURYLTRIONE FOR USE IN RICE CROPS BAYER CROPSCIENCE AG (DE) 2010-12-02 US claimed
WO-2010129345-A2 FOAMABLE PESTICIDE COMPOSITIONS BASF CORPORATION (US) 2010-11-11 WO claimed
WO-2010128003-A2 A METHOD FOR INCREASING THE VIGOR AND/OR CROP YIELD OF AGRICULTURAL PLANTS UNDER ESSENTIALLY NON-EXISTENT PATHOGEN PRESSURE BASF SE (DE) 2010-11-11 WO claimed
WO-2010069763-A2 SYNERGISTIC FUNGICIDAL MIXTURES BASF SE (DE) 2010-06-24 WO claimed
US-20100137137-A1 HERBICIDE/SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 US claimed
WO-2009147205-A2 SYNERGISTIC FUNGICIDAL MIXTURES BASF SE (DE) 2009-12-10 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100311588-A1 SYNERGISTIC HERBICIDAL COMBINATIONS COMPRISING TEMBOTRIONE DDT, TUBB, TUBB3 KDM4E 3705/4885PKM 3273/4885RCE1 3462/4885
US-20220039384-A1 SELECTIVE WEED CONTROL WITH HALAUXIFEN OR 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR DERIVATIVES THEREOF IN VINEYARDS OR PERENNIAL CROPS WEE1, WEE2, HCAR3 KDM4E 165/4885PKM 771/4885RCE1 650/4885
US-20100304973-A1 HERBICIDAL COMBINATIONS COMPRISING TEFURYLTRIONE FOR USE IN RICE CROPS DDT, DHFR, HACL2 KDM4E 2079/4885PKM 1994/4885RCE1 2419/4885
US-20100137137-A1 HERBICIDE/SAFENER COMBINATION DDT, CYP2W1, GAP43 KDM4E 4579/4885PKM 3491/4885RCE1 3721/4885
US-20100322990-A1 METHODS FOR CONTROLLING PESTS DDT, ACHE, PON1 KDM4E 1971/4885PKM 2243/4885RCE1 917/4885
US-20230047569-A1 PESTICIDAL COMPLEX COMPOSITIONS FOR SYNERGISTIC DELIVERY OF PESTICIDAL ACTIVE INGREDIENTS AND METHODS OF SELECTION THEREOF ACHE, DDT, PDE1C KDM4E 1859/4885PKM 1317/4885RCE1 555/4885
US-11185072-B2 Selective weed control with halauxifen or 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl) pyridine-2-carboxylic acid or derivatives thereof in vineyards or perennial crops WEE1, WEE2, HCAR3 KDM4E 165/4885PKM 771/4885RCE1 650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.