Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.34 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.34 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.32 |
| ▸ | IKBKB | O14920 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3329383 | 1.00 | CCNC (0.34) | CCNCCDK8IP6K1IP6K3IP6K2 | |
| SCHEMBL3327333 | 0.90 | PTPN1 (0.36) | RAB9AMEN1KMT2AIKBKBMAPT | |
| SCHEMBL3327323 | 0.90 | PTPN1 (0.36) | RAB9AMEN1KMT2AIKBKBMAPT | |
| SCHEMBL3326900 | 0.88 | CCNC (0.38) | CCNCCDK8IP6K1IP6K3IP6K2 | |
| SCHEMBL3326376 | 0.81 | CCNC (0.35) | CCNCCDK8IP6K1IP6K3IP6K2 | |
| SCHEMBL3326373 | 0.81 | CCNC (0.35) | CCNCCDK8IP6K1IP6K3IP6K2 | |
| SCHEMBL3327312 | 0.78 | IKBKB (0.38) | CCNCCDK8RAB9AMEN1KMT2A | |
| SCHEMBL3327306 | 0.78 | IKBKB (0.38) | CCNCCDK8RAB9AMEN1KMT2A | |
| SCHEMBL3326395 | 0.72 | PDPK1 (0.35) | RAB9AMEN1KMT2AIKBKBHDAC6 | |
| SCHEMBL3328685 | 0.72 | KMT2A (0.35) | CCNCCDK8RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137388-A1 | Therapeutic Pro-Antibiotic Agents and Methods of Use Thereof | DENOVAMED INC. (CA) | 2010-06-03 | — | — | US | claimed |
| US-20100137388-A1 | Therapeutic Pro-Antibiotic Agents and Methods of Use Thereof | DENOVAMED INC. (CA) | 2010-06-03 | — | — | US | disclosed |
| WO-2008128321-A1 | THERAPEUTIC PRO-ANTIBIOTIC AGENTS AND METHODS OF USE THEREOF | DENOVAMED INC. (CA) | 2008-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137388-A1 | Therapeutic Pro-Antibiotic Agents and Methods of Use Thereof | NAT1, NAPEPLD, NR1I2 | CCNC 2580/4885CDK8 4577/4885IP6K1 4628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.