Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.58 |
| ▸ | HTR1A | P08908 | 4/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.58 |
| ▸ | DRD1 | P21728 | 4/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.58 |
| ▸ | DRD3 | P35462 | 4/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiazinamium SCHEMBL4425937 | 0.87 | PTGS1 (0.65) | PTGS1PTGS2CYP2D6CHRM2HTR1A | |
| Thiazinamium SCHEMBL11619269 | 0.85 | PTGS1 (0.63) | PTGS1PTGS2CYP2D6CHRM2HTR1A | |
| Thiazinamium SCHEMBL11617990 | 0.85 | PTGS1 (0.63) | PTGS1PTGS2CYP2D6CHRM2HTR1A | |
| Thiazinamium SCHEMBL635014 | 0.85 | PTGS1 (0.63) | PTGS1PTGS2CYP2D6CHRM2HTR1A | |
| Thiazinamium SCHEMBL29856760 | 0.85 | PTGS1 (0.63) | PTGS1PTGS2CYP2D6CHRM2HTR1A | |
| SCHEMBL13257618 | 0.84 | PTGS1 (0.61) | PTGS1PTGS2CYP2D6CHRM2HTR1A | |
| Bromide SCHEMBL22588368 | 0.83 | PTGS1 (0.59) | PTGS1PTGS2CYP2D6CHRM2HTR1A | |
| Bromide SCHEMBL29392164 | 0.83 | PTGS1 (0.59) | PTGS1PTGS2CYP2D6CHRM2HTR1A | |
| Thiazinamium SCHEMBL11613970 | 0.82 | PTGS1 (0.55) | PTGS1PTGS2CYP2D6CHRM2HTR1A | |
| Bromide SCHEMBL29857119 | 0.81 | PTGS1 (0.58) | PTGS1PTGS2CYP2D6CHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120756-A1 | PHENOTHIAZINE MODULATORS OF H1 RECEPTORS | AUSPEX PHARMACEUTICALS, INC. (US) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120756-A1 | PHENOTHIAZINE MODULATORS OF H1 RECEPTORS | HRH4, HRH2, HRH1 | PTGS1 584/4885PTGS2 577/4885CYP2D6 472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.