Thiazinamium

Thiazinamium

SCHEMBL4425937

CC(CN1c2ccccc2Sc2ccccc21)[N+](C)(C)C

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 3/20 0.65
PTGS2 P35354 2/20 0.65
CYP2D6 P10635 5/20 0.61
CHRM2 P08172 4/20 0.61
HTR1A P08908 4/20 0.61
ADRA2A P08913 4/20 0.61
CHRM1 P11229 4/20 0.61
DRD1 P21728 4/20 0.61
SLC6A2 P23975 4/20 0.61
SLC6A4 P31645 4/20 0.61
ADRA1A P35348 4/20 0.61
OPRM1 P35372 4/20 0.61
DRD3 P35462 4/20 0.61
KCNH2 Q12809 4/20 0.61
ALOX15 P16050 3/20 0.61
HSD17B10 Q99714 3/20 0.61
ALDH1A1 P00352 3/20 0.61
CYP1A2 P05177 3/20 0.61
SLC22A1 O15245 3/20 0.61
LMNA P02545 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiazinamium SCHEMBL11619269 0.98 PTGS1 (0.63) PTGS1PTGS2CYP2D6CHRM2HTR1A
Thiazinamium SCHEMBL11617990 0.98 PTGS1 (0.63) PTGS1PTGS2CYP2D6CHRM2HTR1A
Thiazinamium SCHEMBL29856760 0.98 PTGS1 (0.63) PTGS1PTGS2CYP2D6CHRM2HTR1A
Thiazinamium SCHEMBL635014 0.98 PTGS1 (0.63) PTGS1PTGS2CYP2D6CHRM2HTR1A
Thiazinamium SCHEMBL11613970 0.91 PTGS1 (0.55) PTGS1PTGS2CYP2D6CHRM2HTR1A
SCHEMBL13257618 0.87 PTGS1 (0.61) PTGS1PTGS2CYP2D6CHRM2HTR1A
SCHEMBL3329470 0.87 PTGS1 (0.61) PTGS1PTGS2CYP2D6CHRM2HTR1A
Thiazinamium SCHEMBL29714760 0.86 PTGS1 (0.50) PTGS1PTGS2CYP2D6CHRM2HTR1A
Thiazinamium SCHEMBL29040 0.86 PTGS1 (0.50) PTGS1PTGS2CYP2D6CHRM2HTR1A
Bromide SCHEMBL22588368 0.85 PTGS1 (0.59) PTGS1PTGS2CYP2D6CHRM2HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025082959-A1 A PHENOTHIAZINE-RELATED COMPOUND CONJUGATED TO A PEPTIDE UNIVERSITY OF ULSTER (GB) 2025-04-24 WO claimed
US-20250041208-A1 NEW INJECTABLE COMBINATION FORMULATION NANEXA AB (SE) 2025-02-06 US claimed
EP-4444277-A1 NEW INJECTABLE COMBINATION FORMULATION Nanexa AB (SE) 2024-10-16 EP claimed
EP-4384016-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE Bayer Aktiengesellschaft (DE) 2024-06-19 EP claimed
WO-2023105227-A1 NEW INJECTABLE COMBINATION FORMULATION NANEXA AB (SE) 2023-06-15 WO claimed
WO-2023017120-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE BAYER AKTIENGESELLSCHAFT (DE) 2023-02-16 WO claimed
US-9757376-B2 Pharmaceutical compositions GM PHARMACEUTICALS, INC. (US) 2017-09-12 US claimed
WO-2014186623-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF A CHAGAS DISEASE BIOMED VALLEY DISCOVERIES (US) 2014-11-20 WO claimed
EP-1641446-A1 PHARMACEUTICAL COMPOSITIONS INCLUDING AN ANTIHISTAMINE AND A STIMULANT AND USE THEREOF Pediamed Pharmaceuticals, Inc. (US) 2006-04-05 EP claimed
WO-2004112771-A1 PHARMACEUTICAL COMPOSITIONS INCLUDING AN ANTIHISTAMINE AND A STIMULANT AND USE THEREOF PEDIAMED PHARMACEUTICALS, INC. (US) 2004-12-29 WO claimed
US-20040259809-A1 Pharmaceutical compositions including an antihistamine and a stimulant and method of use thereof PEDIAMED PHARMACEUTICALS, INC. 2004-12-23 US claimed
EP-4633602-A1 NEW PHARMACEUTICAL COMPOSITIONS COMPRISING GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONISTS Nanexa AB (SE) 2025-10-22 EP disclosed
US-20250312275-A1 GAS PHASE DEPOSITION TECHNIQUE FOR PREPARATION OF PHARMACEUTICAL COMPOSITIONS NANEXA AB (SE) 2025-10-09 US disclosed
WO-2025128946-A1 DEVICES AND METHODS OF MAKING AND USE THEREOF THE METHODIST HOSPITAL (US) 2025-06-19 WO disclosed
WO-2025082959-A1 A PHENOTHIAZINE-RELATED COMPOUND CONJUGATED TO A PEPTIDE UNIVERSITY OF ULSTER (GB) 2025-04-24 WO disclosed
WO-2007041677-A2 SOFT TISSUE IMPLANTS AND DRUG COMBINATION COMPOSITIONS, AND USE THEREOF COMBINATORX, INCORPORATED (US) 2007-04-12 WO disclosed
WO-2007041593-A2 ANTI-SCARRING DRUG COMBINATIONS AND USE THEREOF COMBINATORX, INCORPORATED (US) 2007-04-12 WO disclosed
EP-1641446-A1 PHARMACEUTICAL COMPOSITIONS INCLUDING AN ANTIHISTAMINE AND A STIMULANT AND USE THEREOF Pediamed Pharmaceuticals, Inc. (US) 2006-04-05 EP disclosed
WO-2004112771-A1 PHARMACEUTICAL COMPOSITIONS INCLUDING AN ANTIHISTAMINE AND A STIMULANT AND USE THEREOF PEDIAMED PHARMACEUTICALS, INC. (US) 2004-12-29 WO disclosed
US-20040259809-A1 Pharmaceutical compositions including an antihistamine and a stimulant and method of use thereof PEDIAMED PHARMACEUTICALS, INC. 2004-12-23 US disclosed