Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.40 |
| ▸ | NT5E | P21589 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 3/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | DUT | P33316 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8607539 | 0.96 | POLB (0.45) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL2112367 | 0.93 | POLB (0.40) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL2113458 | 0.91 | POLB (0.38) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL7533550 | 0.90 | POLB (0.51) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL332975 | 0.90 | POLB (0.51) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL8607542 | 0.88 | POLB (0.49) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL618136 | 0.88 | POLB (0.36) | POLBABL1RIN1P2RY6NT5E | |
| SCHEMBL2270352 | 0.87 | POLB (0.36) | POLBABL1RIN1NT5EDUT | |
| SCHEMBL2114899 | 0.87 | P2RY6 (0.49) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL8389649 | 0.87 | SMN1; SMN2 (0.39) | POLBABL1RIN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544204-B2 | TIR taste receptors and genes encoding same | FIRMENICH INCORPORATED (US) | 2020-01-28 | — | — | US | disclosed |
| US-20190085051-A1 | T1R TASTE RECEPTORS AND GENES ENCODING SAME | SENOMYX, INC. | 2019-03-21 | — | — | US | disclosed |
| US-9637536-B2 | T1R taste receptors and genes encoding same | SENOMYX, INC. (US) | 2017-05-02 | — | — | US | disclosed |
| US-9273149-B2 | Methods and compositions for determining the purity of chemically synthesized nucleic acids | VERI-Q, INC. (US) | 2016-03-01 | — | — | US | disclosed |
| US-9176130-B2 | Methods of screening T1R1/T1R3 receptors for compounds that modulate umami taste signaling | SENOMYX, INC. (US) | 2015-11-03 | — | — | US | disclosed |
| US-20150299293-A1 | T1R TASTE RECEPTORS AND GENES ENCODING SAME | SENOMYX, INC. | 2015-10-22 | — | — | US | disclosed |
| US-9040247-B2 | Detection of human T1R expressing cells | SENOMYX, INC. (US) | 2015-05-26 | — | — | US | disclosed |
| US-20140329255-A1 | METHODS OF SCREENING T1R1/T1R3 RECEPTORS FOR COMPOUNDS THAT MODULATE UMAMI TASTE SIGNALING | SENOMYX, INC. (US) | 2014-11-06 | — | — | US | disclosed |
| US-8816057-B2 | T1R taste receptors and genes encoding same | SENOMYX, INC. (US) | 2014-08-26 | — | — | US | disclosed |
| US-8815525-B2 | Binding and functional assays that use the T1R3 receptor to screen for taste modulatory compounds | SENOMYX, INC. (US) | 2014-08-26 | — | — | US | disclosed |
| EP-0305201-B1 | Protected biotin derivatives | ZENECA LTD (GB) | 1996-12-04 | — | — | EP | disclosed |
| US-5552535-A | Multiple oligonucleotide containing oligomers and the cleanable linkers used in their preparation | ZENECA LIMITED (GB) | 1996-09-03 | — | — | US | disclosed |
| US-5393877-A | Forming first oligonucleotide on first cleavable link attached to solid support, attaching a cleavable linker moiety, forming second oligonucleotide on the cleavable linker moiety, cleaving to give plurality of oligonucleotides | ZENECA LIMITED (GB) | 1995-02-28 | — | — | US | disclosed |
| EP-0633891-A1 | SYNTHESIS OF OLIGONUCLEOTIDES. | ZENECA LTD (GB) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993020092-A1 | SYNTHESIS OF OLIGONUCLEOTIDES | ZENECA LIMITED (GB) | 1993-10-14 | — | — | WO | disclosed |
| EP-0552185-A1 | SYNTHESIS OF OLIGONUCLEOTIDES | ZENECA LIMITED (GB) | 1993-07-28 | — | — | EP | disclosed |
| WO-1992006103-A1 | SYNTHESIS OF OLIGONUCLEOTIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-16 | — | — | WO | disclosed |
| EP-0202758-B1 | HYBRIDIZATION METHOD AND PROBES THEREFOR | Zeneca Limited (GB) | 1991-09-25 | — | — | EP | disclosed |
| EP-0305201-A2 | Protected biotin derivatives | ZENECA LIMITED (GB) | 1989-03-01 | — | — | EP | disclosed |
| EP-0202758-A1 | Hybridization method and probes therefor | ZENECA LIMITED (GB) | 1986-11-26 | — | — | EP | disclosed |