Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | DUT | P33316 | 2/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL618136 | 0.93 | POLB (0.36) | POLBNT5EABL1RIN1DUT | |
| SCHEMBL2112367 | 0.89 | POLB (0.40) | POLBNT5EABL1RIN1DUT | |
| SCHEMBL2270354 | 0.89 | POLB (0.38) | POLBNT5EABL1RIN1DUT | |
| SCHEMBL2113458 | 0.89 | POLB (0.38) | POLBNT5EABL1RIN1DUT | |
| SCHEMBL332974 | 0.87 | POLB (0.49) | POLBNT5EABL1RIN1DUT | |
| SCHEMBL7199260 | 0.86 | POLB (0.41) | POLBNT5EDUT | |
| SCHEMBL8607539 | 0.84 | POLB (0.45) | POLBNT5EABL1RIN1 | |
| SCHEMBL8389649 | 0.83 | SMN1; SMN2 (0.39) | POLBABL1RIN1 | |
| SCHEMBL618137 | 0.82 | POLB (0.39) | POLBNT5EABL1RIN1DUT | |
| SCHEMBL6328518 | 0.79 | DUT (0.50) | NT5EDUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9273149-B2 | Methods and compositions for determining the purity of chemically synthesized nucleic acids | VERI-Q, INC. (US) | 2016-03-01 | — | — | US | disclosed |
| US-20140193855-A1 | METHODS AND COMPOSITIONS FOR DETERMINING THE PURITY OF CHEMICALLY SYNTHESIZED NUCLEIC ACIDS | VERI-Q, INC. (US) | 2014-07-10 | — | — | US | disclosed |
| US-8173377-B2 | Methods and compositions for determining the purity of chemically synthesized nucleic acids | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-05-08 | — | — | US | disclosed |
| US-20110190154-A1 | METHODS AND COMPOSITIONS FOR DETERMINING THE PURITY OF CHEMICALLY SYNTHESIZED NUCLEIC ACIDS | AGRIS PAUL F | 2011-08-04 | — | — | US | disclosed |
| US-6929907-B2 | Used for detecting incomplete deprotection of a synthetic oligonucleotide by immunoassay | NORTH CAROLINA STATE UNIVERSITY (US) | 2005-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190154-A1 | METHODS AND COMPOSITIONS FOR DETERMINING THE PURITY OF CHEMICALLY SYNTHESIZED NUCLEIC ACIDS | RNGTT, NOP2, DCLRE1B | POLB 34/4885NT5E 208/4885ABL1 3901/4885 |
| US-20140193855-A1 | METHODS AND COMPOSITIONS FOR DETERMINING THE PURITY OF CHEMICALLY SYNTHESIZED NUCLEIC ACIDS | RNGTT, NOP2, DCLRE1B | POLB 34/4885NT5E 208/4885ABL1 3901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.