Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phenolsulphonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 7/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.36 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.36 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenolsulphonic Acid SCHEMBL3178625 | 0.86 | LMNA (0.47) | HIF1ALMNAHPGDHSD17B10MYC | |
| Phenolsulphonic Acid SCHEMBL8352680 | 0.86 | LMNA (0.46) | HIF1ALMNAHPGDHSD17B10MYC | |
| Diethylamine SCHEMBL28384655 | 0.86 | LMNA (0.57) | HIF1ALMNAHPGDHSD17B10MYC | |
| Phenolsulphonic Acid SCHEMBL3324950 | 0.84 | LMNA (0.44) | HIF1ALMNAHPGDHSD17B10MYC | |
| Phenolsulphonic Acid SCHEMBL29449532 | 0.84 | SMN1; SMN2 (0.46) | HIF1ALMNAHPGDHSD17B10MYC | |
| Phenolsulphonic Acid SCHEMBL18274 | 0.84 | SMN1; SMN2 (0.46) | HIF1ALMNAHPGDHSD17B10MYC | |
| Phenolsulphonic Acid SCHEMBL11154671 | 0.84 | SMN1; SMN2 (0.46) | HIF1ALMNAHPGDHSD17B10MYC | |
| Phenolsulphonic Acid SCHEMBL3173401 | 0.82 | AURKA (0.46) | HIF1ALMNAHPGDHSD17B10MYC | |
| Phenolsulphonic Acid SCHEMBL9491240 | 0.82 | AURKA (0.44) | HIF1ALMNAHPGDHSD17B10MYC | |
| Phenolsulphonic Acid SCHEMBL20815894 | 0.82 | AURKA (0.44) | HIF1ALMNAHPGDHSD17B10MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111351886-B | Method for determining impurity and main medicine content in phenol sulfoethylamine medicine | 成都平和安康医药科技有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-111351886-B | Method for determining impurity and main medicine content in phenol sulfoethylamine medicine | 成都平和安康医药科技有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-111351886-A | Method for determining impurities contained in etamsylate and content of main drug thereof | 成都平和安康医药科技有限公司 | 2020-06-30 | — | — | CN | disclosed |
| US-7842104-B2 | Method of manufacturing solid electrolytic capacitor | SANYO ELECTRIC CO., LTD. (JP) | 2010-11-30 | — | — | US | disclosed |
| US-20100127205-A1 | METHOD OF MANUFACTURING SOLID ELECTROLYTIC CAPACITOR | SANYO ELECTRIC CO., LTD. (JP) | 2010-05-27 | — | — | US | disclosed |