⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5686317 | 0.76 | TSHR (0.31) | — | |
| SCHEMBL5692307 | 0.73 | TSHR (0.32) | — | |
| SCHEMBL11424423 | 0.70 | — | — | |
| SCHEMBL5052099 | 0.68 | TSHR (0.32) | — | |
| SCHEMBL7864822 | 0.68 | TSHR (0.33) | — | |
| SCHEMBL5050614 | 0.68 | LMNA (0.32) | — | |
| SCHEMBL5050678 | 0.67 | TSHR (0.42) | — | |
| SCHEMBL975993 | 0.66 | — | — | |
| SCHEMBL20787616 | 0.66 | LMNA (0.33) | — | |
| SCHEMBL1720452 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2148742-B1 | SEPARATION OF N,N,N'-TRIMETHYLBISAMINOETHYLETHER FROM MIXTURES COMPRISING TERTIARY AMINES OR TERTIARY AMINOALKYLETHERS | HUNTSMAN INT LLC (US) | 2014-04-16 | — | — | EP | disclosed |
| EP-2438039-B1 | A METHOD FOR SEPARATING N,N-DIALKYLBISAMINOALKYLETHER FROM MIXTURES COMPRISING N,N-DIALKYLBISAMINOALKYLETHER AND AT LEAST ONE OF N,N,N'-TRIALKYLBISAMINOALKYLETHER AND N,N,N',N'-TETRAALKYLBISAMINOALKYLETHER | HUNTSMAN CORP HUNGARY ZRT (HU) | 2013-07-31 | — | — | EP | disclosed |
| US-8232223-B2 | Separation of N,N,N′-trimethylbisamino-ethylether from mixtures comprising tertiary amines or tertiary aminoalkylethers | HUNTSMAN INTERNATIONAL LLC (US) | 2012-07-31 | — | — | US | disclosed |
| US-20100144517-A1 | Separation from catalyst precursor N,N,N',N'-tetramethylbisaminoethyl ether via transamidation; azeotropic composition comprising N,N,N'-trimethylbisaminoethylether and monoethanolamine | HUNTSMAN INTERNATIONAL LLC. (US) | 2010-06-10 | — | — | US | disclosed |