⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423657 | 0.79 | — | — | |
| SCHEMBL28486940 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL28486687 | 0.70 | MEN1 (0.46) | — | |
| SCHEMBL9572829 | 0.67 | — | — | |
| SCHEMBL2534570 | 0.67 | — | — | |
| Ammonia Solution, Strong SCHEMBL28914391 | 0.67 | — | — | |
| SCHEMBL1908087 | 0.67 | — | — | |
| SCHEMBL29061272 | 0.65 | — | — | |
| SCHEMBL28611936 | 0.63 | — | — | |
| SCHEMBL28609350 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097594-B2 | Macrolides and ketolides having antimicrobial activity | WOCKHARDT LTD. (IN) | 2012-01-17 | — | — | US | disclosed |
| US-20090247478-A1 | Novel macrolides and ketolides having antimicrobial activity | SINDKHEDKAR MILIND DATTATRAYA | 2009-10-01 | — | — | US | disclosed |
| US-7572753-B2 | Tetrazole fungicides | CHEMTURA CORPORATION (US) | 2009-08-11 | — | — | US | disclosed |
| US-20070060631-A1 | 2-cyanomethyl-5-(3-substituted phenyl or 5-substituted thien-2-yl)-2H-tetrazoles; agricultural fungicides such as for rice blast | CROMPTON COLORS INCORPORATED | 2007-03-15 | — | — | US | disclosed |
| US-4338452-A | 1-and 2-(1-Alkyl-1H-tetrazol-5-yl-methyl)-1H-tetrazol-5-thiols and 1-cyanomethyl tetrazole-5-thiol | ELI LILLY AND COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| EP-0048166-A1 | Bicyclic 1-oxa-beta-lactam compounds, their preparation and pharmaceutical formulations containing them | ELI LILLY AND COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |
| EP-0048167-A2 | Bis-tetrazolemethyl thiols and their preparation | ELI LILLY AND COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |
| EP-0048168-A2 | 7-Acylamino cephalosporin compounds, their preparation and pharmaceutical formulations containing them | ELI LILLY AND COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |
| US-4301282-A | 1-Oxa-β-lactam antibiotics | ELI LILLY AND COMPANY (US) | 1981-11-17 | — | — | US | disclosed |