⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL247253 | 0.97 | — | — | |
| SCHEMBL30083791 | 0.82 | — | — | |
| SCHEMBL15950989 | 0.71 | COMT (0.60) | — | |
| SCHEMBL23400943 | 0.70 | — | — | |
| SCHEMBL29766487 | 0.70 | — | — | |
| SCHEMBL4914745 | 0.69 | — | — | |
| SCHEMBL14938176 | 0.67 | CYP1A2 (0.53) | — | |
| SCHEMBL13212232 | 0.67 | SLC9A1 (0.41) | — | |
| SCHEMBL19026752 | 0.67 | — | — | |
| SCHEMBL8582470 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 710 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120040366-A | Preparation method of topramezone intermediate and preparation method of topramezone | 合肥星宇化学有限责任公司 | 2025-05-27 | — | — | CN | claimed |
| CN-120025324-A | Topramezone and its preparation method Process for synthesizing ketone | 安徽丰乐农化有限责任公司 | 2025-05-23 | — | — | CN | claimed |
| CN-119684212-A | Preparation method of 1-methyl-5-hydroxypyrazole | 苏州乔贝迪医药科技有限公司 | 2025-03-25 | — | — | CN | claimed |
| CN-119684211-A | Synthesis method of compound 4-bromo-5-methoxy-1-methyl-1H-pyrazole | 上海毕得医药科技股份有限公司 | 2025-03-25 | — | — | CN | claimed |
| CN-119591489-A | Synthesis method of tri-polyethylene glycol-acetic acid | 凯美克(上海)医药科技有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-119371413-A | Topramezone and its preparation method Process for the preparation of ketones | 安徽丰乐农化有限责任公司 | 2025-01-28 | — | — | CN | claimed |
| US-20240409557-A1 | 5,6-FUSED AND 6,6-FUSED BICYCLIC ALCOHOLS AND ETHERS AND COMPOSITIONS FOR USE AS 15-PROSTAGLANDIN DEHYDROGENASE MODULATORS | AMGEN INC. (US) | 2024-12-12 | — | — | US | claimed |
| CN-119096982-A | Topramezone-containing topramezone Ketone pesticide composition | 帕潘纳(北京)科技有限公司 | 2024-12-10 | — | — | CN | claimed |
| CN-117551090-A | Method for synthesizing topramezone by photocatalysis | 江苏农牧科技职业学院 | 2024-02-13 | — | — | CN | claimed |
| CN-116947837-A | Topramezone intermediate and preparation method thereof | 帕潘纳(北京)科技有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-103788083-A | Method for preparing herbicide topramezone | UNIV CHINA PHARMA | 2014-05-14 | — | — | CN | claimed |
| JP-4669612-B2 | — | — | 2011-04-13 | — | — | JP | claimed |
| CN-1315381-C | Herbicidal mixtures comprising safeners | BASF AG (DE) | 2007-05-16 | — | — | CN | claimed |
| CN-1761394-A | Synergistically acting herbicidal mixtures | BASF AG (DE) | 2006-04-19 | — | — | CN | claimed |
| CN-1761393-A | Herbicidal mixtures comprising a safener | BASF AG (DE) | 2006-04-19 | — | — | CN | claimed |
| US-20030109717-A1 | Preparation of substituted hydroxypyrazoles | GOTZ NORBERT (DE) | 2003-06-12 | — | — | US | claimed |
| JP-2002529454-A | — | — | 2002-09-10 | — | — | JP | claimed |
| EP-1127050-A1 | METHOD FOR PRODUCING 1-SUBSTITUTED 5-HYDROXYPYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 2001-08-29 | — | — | EP | claimed |
| WO-2000027821-A1 | METHOD FOR PRODUCING 1-SUBSTITUTED 5-HYDROXYPYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-18 | — | — | WO | claimed |
| CN-1248255-A | 3-heterocyclyl-substituted benzoyl derivatives | BASF AG (DE) | 2000-03-22 | — | — | CN | claimed |