Ethylene Glycol

Ethylene Glycol

SCHEMBL3333475

CCOCCBr.OCCO

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.60
TSHR P16473 4/20 0.37
MAPK1 P28482 1/20 0.33
THRB P10828 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HTT P42858 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL57457 0.88
SCHEMBL27400355 0.82 ALDH1A1 (0.43) ALDH1A1TSHRTHRBMAPT
SCHEMBL9171181 0.82 ALDH1A1 (0.43) ALDH1A1TSHRTHRBMAPT
SCHEMBL1782203 0.82
Ethylene Glycol SCHEMBL28322256 0.82 ALDH1A1 (0.75) ALDH1A1TSHRMAPK1THRBMEN1
Ethylene Glycol SCHEMBL14635451 0.82 ALDH1A1 (0.75) ALDH1A1TSHRMAPK1THRBMEN1
Ether SCHEMBL8896364 0.79
2-Ethoxyethanol SCHEMBL8056895 0.79 ALDH1A1 (0.93) ALDH1A1TSHRMAPK1THRBMEN1
Ether SCHEMBL20185732 0.79 ALDH1A1 (0.71) ALDH1A1TSHRMAPK1THRBMEN1
Ether SCHEMBL8961469 0.79 ALDH1A1 (0.38) ALDH1A1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100136300-A1 CURABLE COMPOSITION, INK COMPOSITION, INKJET RECORDING METHOD, PRINTED MATERIAL, METHOD OF PRODUCING PLANOGRAPHIC PRINTING PLATE, PLANOGRAPHIC PRINTING PLATE AND OXETANE COMPOUND FUJIFILM CORPORATION (JP) 2010-06-03 US disclosed
EP-1757635-B1 Curable ink comprising modified oxetane compound FUJIFILM CORP (JP) 2008-10-08 EP disclosed
US-20070049651-A1 Curable composition, ink composition, inkjet recording method, printed material, method of producing planographic printing plate, planographic printing plate, and oxcetane compound FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
EP-1757635-A1 Curable modified oxetane compound and ink composition comprising it Fuji Photo Film Co., Ltd. (JP) 2007-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100136300-A1 CURABLE COMPOSITION, INK COMPOSITION, INKJET RECORDING METHOD, PRINTED MATERIAL, METHOD OF PRODUCING PLANOGRAPHIC PRINTING PLATE, PLANOGRAPHIC PRINTING PLATE AND OXETANE COMPOUND CCNT1, ACVR2B, ACVR1B ALDH1A1 1249/4885TSHR 4701/4885MAPK1 486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.