SCHEMBL333387

SCHEMBL333387

O=C=Nc1ccc(C(N=C=O)(c2ccccc2)c2ccc(N=C=O)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 3/20 0.42
▸ TSHR P16473 1/20 0.42
▸ MAPK1 P28482 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.36
▸ TRPA1 O75762 1/20 0.34
▸ MIF P14174 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ GABRA1 P14867 1/20 0.32
▸ GABRB2 P47870 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3611392 1.00 CYP3A4 (0.42) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL3517726 0.86 KCNN4 (0.36) TSHRMAPK1CYP1A2
SCHEMBL3851167 0.82 CYP3A4 (0.47) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL28772905 0.82 CYP3A4 (0.47) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL28473582 0.82 CYP3A4 (0.47) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL6402756 0.82 CYP3A4 (0.40) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL28153949 0.80 TSHR (0.32) TSHRCYP1A2
SCHEMBL28470737 0.79 CYP3A4 (0.48) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL30295335 0.79 ESR1 (0.48) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL7191356 0.76 CYP3A4 (0.48) CYP3A4TSHRMAPK1TDP1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7786243-B2 Polyurea and polyurethane compositions for golf equipment ACUSHNET COMPANY (US) 2010-08-31 — — US claimed
US-20100125002-A1 RESIN COMPOSITIONS INCORPORATING MODIFIED POLYISOCYANATE AND METHOD FOR THEIR MANUFACTURE AND USE TAYLOR MADE GOLF COMPANY, INC. 2010-05-20 — — US claimed
US-20090149278-A1 Polyurea and Polyurethane Compositions for Golf Equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2009-06-11 — — US claimed
US-7131915-B2 Three-layer-cover golf ball ACUSHNET COMPANY (US) 2006-11-07 — — US claimed
US-20040235587-A1 Three-layer-cover golf ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-25 — — US claimed
CN-114341230-B Polyester polyol based on tris (hydroxymethyl) phosphine oxide and resin composition obtained therefrom 亨茨曼国际有限公司 2024-07-12 — — CN disclosed
US-20240228710-A1 Polymer Articles For A Coolant Fluid Circuit in Electric Vehicles CELANESE INTERNATIONAL CORPORATION 2024-07-11 — — US disclosed
US-12023554-B2 Method of golf ball manufacture employing ultrasonic welding, and resulting golf ball and golf ball components and/or layers Masion de Golf (US) 2024-07-02 — — US disclosed
US-11975241-B2 Golf ball TAYLOR MADE GOLF COMPANY, INC. (US) 2024-05-07 — — US disclosed
CN-117916082-A Laminate and method for producing laminate 富士胶片株式会社 2024-04-19 — — CN disclosed
US-20240082645-A1 MULTI-COLOR GOLF BALL TAYLOR MADE GOLF COMPANY, INC. (US) 2024-03-14 — — US disclosed
US-20240058654-A1 GOLF BALL WITH SOFTER FEEL AND HIGHER IRON SPIN TAYLOR MADE GOLF COMPANY, INC. (US) 2024-02-22 — — US disclosed
US-20030212240-A1 Polyurethane compositions for golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-11-13 — — US disclosed
US-20030096936-A1 Golf balls comprising light stable materials and methods of making the same JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-05-22 — — US disclosed
EP-0595356-A2 Cationic electrocoating composition Nippon Paint Co., Ltd. (JP) 1994-05-04 — — EP disclosed
EP-0255010-B1 INTUMESCENT MATERIALS, COATINGS AND CONSTRUCTION ELEMENTS MADE WITH THESE MATERIALS, AND PROCESS FOR THE PREPARATION OF THESE INTUMESCENT MATERIALS BAYER AG (DE) 1991-04-24 — — EP disclosed
US-4857364-A Intumescent compositions and the use thereof BAYER AKTIENGESELLSCHAFT (DE) 1989-08-15 — — US disclosed
US-4831062-A Preparation of intumescent materials for coatings and building elements BAYER AKTIENGESELLSCHAFT (DE) 1989-05-16 — — US disclosed
US-4778844-A SALT FORMATION BY BASIFICATION OF ACIDIC PHOSPHOROUS COMPOUNDS; THEN REACTION OF POLYOL AND POLYISOCYANATE BLOUNT DAVID H (US) 1988-10-18 — — US disclosed
EP-0274068-A2 Intumescent masses and their use BAYER AG (DE) 1988-07-13 — — EP disclosed
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