Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3851167 | 0.87 | CYP3A4 (0.47) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL333387 | 0.82 | CYP3A4 (0.42) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL3611392 | 0.82 | CYP3A4 (0.42) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL28473582 | 0.80 | CYP3A4 (0.47) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL28772905 | 0.80 | CYP3A4 (0.47) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL11076368 | 0.79 | CYP3A4 (0.40) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL30295335 | 0.77 | ESR1 (0.48) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL28470737 | 0.77 | CYP3A4 (0.48) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL7191356 | 0.74 | CYP3A4 (0.48) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL245090 | 0.72 | MIF (0.55) | CYP3A4TSHRMAPK1TDP1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849667-B2 | Mixing 0.1-30 parts by weight carbon dioxide to 100 parts by weight urethane-based thermoplastic elastomer composition in molten state, cooling, depressurizing, foaming; use of carbon dioxide in place of fluorochlorohydrocarbon prevents pollution | MITSUI CHEMICALS, INC. (JP) | 2005-02-01 | — | — | US | disclosed |
| US-20020193459-A1 | Foam of thermoplastic urethane elastomer composition and process for producing the foam | MITSUI CHEMICALS, INC. (JP) | 2002-12-19 | — | — | US | disclosed |
| EP-1266928-A1 | FOAM OF THERMOPLASTIC URETHANE ELASTOMER COMPOSITION AND PROCESS FOR PRODUCING THE FOAM | Mitsui Chemicals, Inc. (JP) | 2002-12-18 | — | — | EP | disclosed |