Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | KDM5C | P41229 | 1/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 4/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 3/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19423 | 0.97 | — | — | |
| SCHEMBL6849888 | 0.94 | EGLN1 (0.42) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL399043 | 0.94 | EGLN1 (0.42) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL597441 | 0.94 | EGLN1 (0.42) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL2124398 | 0.94 | EGLN1 (0.42) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL2920160 | 0.94 | EGLN1 (0.42) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL596299 | 0.94 | EGLN1 (0.42) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL2927264 | 0.94 | EGLN1 (0.42) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL108609 | 0.94 | EGLN1 (0.42) | EGLN1KDM4EKDM6BKDM5CPHF8 | |
| SCHEMBL4474843 | 0.94 | EGLN1 (0.42) | EGLN1KDM4EKDM6BKDM5CPHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701807-B2 | Process for making polymers having nanostructures incorporated into the matrix of the polymer | PPG INDUSTRIES OHIO, INC. (US) | 2017-07-11 | — | — | US | claimed |
| EP-1871824-B1 | COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION | BRIDGESTONE CORP (JP) | 2017-03-01 | — | — | EP | claimed |
| US-9403969-B2 | Compounding silica-reinforced rubber with low volatile organic compound (VOC) emission | BRIDGESTONE CORPORATION (JP) | 2016-08-02 | — | — | US | claimed |
| US-20160083556-A1 | PROCESS FOR MAKING POLYMERS HAVING NANOSTRUCTURES INCORPORATED INTO THE MATRIX OF THE POLYMER | PPG INDUSTRIES OHIO, INC. | 2016-03-24 | — | — | US | claimed |
| US-8980387-B2 | Method of coating a surface and article incorporating coated surface | GENERAL ELECTRIC COMPANY (US) | 2015-03-17 | — | — | US | claimed |
| CN-104093812-A | Method of delaying crosslinking in well treatment operation | BAKER HUGHES INC | 2014-10-08 | — | — | CN | claimed |
| US-20140011924-A1 | COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION | BRIDGESTONE CORPORATION (JP) | 2014-01-09 | — | — | US | claimed |
| US-20130108810-A1 | METHOD OF COATING A SURFACE AND ARTICLE INCORPORATING COATED SURFACE | GENERAL ELECTRIC COMPANY (US) | 2013-05-02 | — | — | US | claimed |
| US-8288474-B2 | Compounding silica-reinforced rubber with low volatile organic compound (VOC) emission | BRIDGESTONE CORPORATION (JP) | 2012-10-16 | — | — | US | claimed |
| US-20120231279-A1 | PROCESS FOR MAKING POLYMERS HAVING NANOSTRUCTURES INCORPORATED INTO THE MATRIX OF THE POLYMER | PPG INDUSTRIES OHIO, INC. (US) | 2012-09-13 | — | — | US | claimed |
| US-20060094912-A1 | toluene and o-xylene are chlorinated in the presence of a catalyst combination produced by (1) a combination of a salt of of 4-12 metal, lanthanide, actinides; and an organic acidic counterion; (2) an organic sulfur | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2006-05-04 | — | — | US | claimed |
| US-7012166-B2 | Catalyst composition and method for chlorinating aromatic compounds | GENERAL ELECTRIC COMPANY (US) | 2006-03-14 | — | — | US | claimed |
| WO-2006009662-A2 | METHODS FOR GENERATING AND RECYCLING METAL HALIDE CATALYST COMPOSITIONS FOR AROMATIC RING ALOGENATION | GENERAL ELECTRIC COMPANY (US) | 2006-01-26 | — | — | WO | claimed |
| US-20050283034-A1 | Methods for recycling catalyst compositions for aromatic ring halogenation | GENERAL ELECTRIC COMPANY | 2005-12-22 | — | — | US | claimed |
| US-6844379-B2 | Organic component comprises long-chain cycloaliphatic epoxy resin, short-chain cycloaliphatic epoxy resin, cyanate ester, lewis acid catalyst; useful in die attach adhesives, underfills, encapsulants, via fills, prepreg binders | HONEYWELL INTERNATIONAL INC. (US) | 2005-01-18 | — | — | US | claimed |
| WO-2004082826-A2 | CATALYST COMPOSITION AND METHOD FOR CHLORINATING AROMATIC COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2004-09-30 | — | — | WO | claimed |
| US-20040186329-A1 | Catalyst composition and method for chlorinating aromatic compounds | GENERAL ELECTRIC COMPANY | 2004-09-23 | — | — | US | claimed |
| US-20030166746-A1 | Organic component comprises long-chain cycloaliphatic epoxy resin, short-chain cycloaliphatic epoxy resin, cyanate ester, lewis acid catalyst; useful in die attach adhesives, underfills, encapsulants, via fills, prepreg binders | ZHOU XIAO-QI (US) | 2003-09-04 | — | — | US | claimed |
| US-6489380-B1 | MIXTURES OF FILLERS, HETEROCYLIC ETHERS, NITRILES, LEWIS ACID CATALYSTS AND/OR BROWNSTED ACIDS HAVING HIGH FLEXIBILITY AND HERMETIC SEALING, USED IN SEMICONDUCTOR APPLICATIONS | JOHNSON MATTHEY ELECTRONICS, INC. | 2002-12-03 | — | — | US | claimed |
| US-H626-H | CONTROLLED PARTICLE SIZE DISTRIBUTION AND CRYSTAL STRUCTURE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1989-04-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050283034-A1 | Methods for recycling catalyst compositions for aromatic ring halogenation | PRKACG, HCN4, CLIC4 | EGLN1 3431/4885KDM4E 659/4885KDM6B 1350/4885 |
| US-20040186329-A1 | Catalyst composition and method for chlorinating aromatic compounds | PRKACA, CLK4, PRKACG | EGLN1 2255/4885KDM4E 1380/4885KDM6B 3084/4885 |
| US-20060094912-A1 | toluene and o-xylene are chlorinated in the presence of a catalyst combination produced by (1) a combination of a salt of of 4-12 metal, lanthanide, actinides; and an organic acidic counterion; (2) an organic sulfur | CLIC4, CLK4, PRKACA | EGLN1 3102/4885KDM4E 855/4885KDM6B 2561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.