Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | PNMT | P11086 | 3/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | BAD | Q92934 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23944932 | 0.77 | PARP1 (0.46) | CES1PNMTBCL2L1BADTSHR | |
| SCHEMBL23674439 | 0.76 | HTR2C (0.38) | HTR2AHTR2CHTR2BPNMTADRA2A | |
| SCHEMBL7271975 | 0.73 | EGFR (0.42) | ADRA2AADRA2BADRA2CBCL2L1BAD | |
| SCHEMBL2534784 | 0.71 | PNMT (0.55) | HTR2AHTR2CHTR2BPNMTADRA2A | |
| SCHEMBL22632718 | 0.69 | HTR2A (0.41) | HTR2AHTR2CHTR2BPNMTADRA2A | |
| SCHEMBL5399458 | 0.68 | CES1 (0.38) | CES1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7444249 | 0.66 | — | — | |
| SCHEMBL3976079 | 0.66 | — | — | |
| SCHEMBL24011796 | 0.66 | — | — | |
| SCHEMBL22493786 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 312 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856201-B1 | PROCESS FOR CROSSLINKING POLYMER WITH LOW VOC-PRODUCING SILANE CROSSLINKER | MOMENTIVE PERFORMANCE MAT INC (US) | 2019-08-14 | — | — | EP | claimed |
| EP-2241583-B1 | CROSSLINKABLE SILANE-TERMINATED POLYMER AND SEALANT COMPOSITION MADE WITH SAME | MOMENTIVE PERFORMANCE MAT INC (US) | 2018-10-03 | — | — | EP | claimed |
| EP-1888663-B1 | CROSSLINKABLE SILANE-TERMINATED POLYMER AND SEALANT COMPOSITION MADE WITH SAME | MOMENTIVE PERFORMANCE MAT INC (US) | 2018-08-08 | — | — | EP | claimed |
| EP-2708546-B1 | Halo-Functional Silane, process for its preparation, rubber composition containing same and articles manufactured therefrom | MOMENTIVE PERFORMANCE MAT INC (US) | 2016-01-06 | — | — | EP | claimed |
| EP-1858968-B1 | FILLER TREATMENTS UTILIZING LOW VOC SILANES | MOMENTIVE PERFORMANCE MAT INC (US) | 2015-12-09 | — | — | EP | claimed |
| EP-2708546-A1 | Halo-Functional Silane, process for its preparation, rubber composition containing same and articles manufactured therefrom | Momentive Performance Materials Inc. (US) | 2014-03-19 | — | — | EP | claimed |
| EP-2207782-B1 | HALO-FUNCTIONAL SILANE, PROCESS FOR ITS PREPARATION, RUBBER COMPOSITION CONTAINING SAME AND ARTICLES MANUFACTURED THEREFROM | MOMENTIVE PERFORMANCE MAT INC (US) | 2014-02-26 | — | — | EP | claimed |
| EP-1270581-B1 | Blocked mercaptosilane coupling agents for filled rubbers | MOMENTIVE PERFORMANCE MAT INC (US) | 2014-02-19 | — | — | EP | claimed |
| US-8158812-B2 | Diol-derived organofunctional silane and compositions containing same | Momentive Performance Marerials Inc. (US) | 2012-04-17 | — | — | US | claimed |
| US-20110213074-A1 | DIOL-DERIVED ORGANOFUNCTIONAL SILANE AND COMPOSITIONS CONTAINING SAME | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-09-01 | — | — | US | claimed |
| US-20060063879-A1 | Tire with low volatile alcohol emission rubber tread with compositional limitations | GOODYEAR TIRE & RUBBER COMPANY, THE | 2006-03-23 | — | — | US | claimed |
| WO-2006019963-A1 | DIOL-DERIVED ORGANOFUNCTIONAL SILANE AND COMPOSITIONS CONTAINING SAME | GENERAL ELECTRIC COMPANY (US) | 2006-02-23 | — | — | WO | claimed |
| US-20060036034-A1 | Diol-derived organofunctional silane and compositions containing same | GENERAL ELECTRIC COMPANY | 2006-02-16 | — | — | US | claimed |
| US-20050245753-A1 | Cyclic diol-derived blocked mercaptofunctional silane compositions | MOMENTIVE PERFORMANCE MATERIALS INC. | 2005-11-03 | — | — | US | claimed |
| CN-1643145-A | Purification methods for oligonucleotides and their analogs | AVECIA BIOTECHNOLOGY INC (US) | 2005-07-20 | — | — | CN | claimed |
| US-20030199619-A1 | Blocked mercaptosilane hydrolyzates as coupling agents for mineral-filled elastomer compositions | CROMPTON CORPORATION | 2003-10-23 | — | — | US | claimed |
| EP-0877592-B1 | HAIR CONDITIONING COMPOSITIONS | PROCTER & GAMBLE (US) | 2002-09-18 | — | — | EP | claimed |
| EP-0877591-B1 | HAIR CONDITIONING COMPOSITIONS | PROCTER & GAMBLE (US) | 2002-09-18 | — | — | EP | claimed |
| US-6106814-A | CATIONIC, CROSSLINKED POLYMER HAVING DIALKYLAMINOALKYL (METH)ACRYLATE OR QUATERNARY MONOMER(S); POLYOXYALKYLENE GLYCOL, SALT, AND POLAR SOLVENT; ATOMIZABLE, LEAVE-ON HAIR | THE PROCTER & GAMBLE COMPANY (US) | 2000-08-22 | — | — | US | claimed |
| US-3966711-A | 4-Alkyl-1,4-diaza-5-oxo-cycloheptanes and their 1-oxyls | CIBA-GEIGY CORPORATION (US) | 1976-06-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110213074-A1 | DIOL-DERIVED ORGANOFUNCTIONAL SILANE AND COMPOSITIONS CONTAINING SAME | OR51E2, FANCF, DDT | CES1 1920/4885HTR2A 3675/4885HTR2C 3086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.