Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 15/20 | 0.64 |
| ▸ | FAAH | O00519 | 9/20 | 0.64 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | AADAC | P22760 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 2/20 | 0.47 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2763760 | 0.83 | EPHX2 (0.50) | EPHX2FAAHACACBFPR2PROKR1 | |
| SCHEMBL2763242 | 0.83 | SMN1; SMN2 (0.56) | EPHX2FAAHACACBFPR2PROKR1 | |
| SCHEMBL2089684 | 0.82 | EPHX2 (0.60) | EPHX2FAAHMMP2MMP13AADAC | |
| SCHEMBL3339119 | 0.82 | EPHX2 (0.47) | EPHX2FAAHMMP2MMP13ACACB | |
| SCHEMBL2763580 | 0.82 | EPHX2 (0.50) | EPHX2FAAHACACBSCN9A | |
| SCHEMBL6097817 | 0.78 | EPHX2 (0.56) | EPHX2FAAHMMP2MMP13AADAC | |
| SCHEMBL2056114 | 0.77 | HRH3 (0.58) | EPHX2FAAHMMP2MMP13KCNH2 | |
| SCHEMBL2089682 | 0.77 | EPHX2 (0.54) | EPHX2FAAHMMP2MMP13AADAC | |
| SCHEMBL20588166 | 0.77 | EPHX2 (0.50) | EPHX2FAAHMMP2MMP13ACACB | |
| SCHEMBL3028128 | 0.75 | POLB (0.56) | EPHX2FAAHMMP2MMP13FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8592595-B2 | Preparation of (N-heterocyclyl) aryl ethers | SALTIGO GMBH (DE) | 2013-11-26 | — | — | US | claimed |
| US-20100152454-A1 | PREPARATION OF (N-HETEROCYCLYL) ARYL ETHERS | SALTIGO GMBH (DE) | 2010-06-17 | — | — | US | claimed |
| US-8592595-B2 | Preparation of (N-heterocyclyl) aryl ethers | SALTIGO GMBH (DE) | 2013-11-26 | — | — | US | disclosed |
| US-20100152454-A1 | PREPARATION OF (N-HETEROCYCLYL) ARYL ETHERS | SALTIGO GMBH (DE) | 2010-06-17 | — | — | US | disclosed |