SCHEMBL2763580

SCHEMBL2763580

CC(=O)NN1CCC(Oc2ccccc2)CC1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 6/20 0.50
CARM1 Q86X55 1/20 0.50
PRMT6 Q96LA8 1/20 0.50
ACACB O00763 1/20 0.47
USP5 P45974 1/20 0.46
FAAH O00519 1/20 0.46
NAMPT P43490 1/20 0.45
CHRM2 P08172 1/20 0.45
CHRM3 P20309 1/20 0.45
SCN9A Q15858 2/20 0.45
FFAR4 Q5NUL3 1/20 0.44
SCD5 Q86SK9 1/20 0.44
SRD5A1 P18405 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2763242 0.87 SMN1; SMN2 (0.56) EPHX2ACACBFAAH
SCHEMBL2763760 0.87 EPHX2 (0.50) EPHX2ACACBFAAH
SCHEMBL7486941 0.82 USP30 (0.47) EPHX2CARM1PRMT6USP5FAAH
SCHEMBL3334541 0.82 EPHX2 (0.64) EPHX2ACACBFAAHSCN9A
SCHEMBL2091338 0.80 EPHX2 (0.57) EPHX2CARM1PRMT6NAMPTSCD5
SCHEMBL3339119 0.77 EPHX2 (0.47) EPHX2ACACBFAAHSCN9A
SCHEMBL15492542 0.76 SLC18A3 (0.51) CARM1PRMT6
SCHEMBL4785267 0.76 EPHX2 (0.48) EPHX2FAAHCHRM3SRD5A1
SCHEMBL5271411 0.76 EPHX2 (0.59) EPHX2NAMPTSCD5SRD5A1
SCHEMBL4578845 0.74 EPHX2 (0.58) EPHX2NAMPTFFAR4SCD5SRD5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592595-B2 Preparation of (N-heterocyclyl) aryl ethers SALTIGO GMBH (DE) 2013-11-26 US claimed
US-20100152454-A1 PREPARATION OF (N-HETEROCYCLYL) ARYL ETHERS SALTIGO GMBH (DE) 2010-06-17 US claimed
EP-2179988-A1 Producing (N-heterocyclic) aryl ethers Saltigo GmbH (DE) 2010-04-28 EP claimed
US-8592595-B2 Preparation of (N-heterocyclyl) aryl ethers SALTIGO GMBH (DE) 2013-11-26 US disclosed
US-20100152454-A1 PREPARATION OF (N-HETEROCYCLYL) ARYL ETHERS SALTIGO GMBH (DE) 2010-06-17 US disclosed
EP-2179988-A1 Producing (N-heterocyclic) aryl ethers Saltigo GmbH (DE) 2010-04-28 EP disclosed